ArticleEMBO reports2021
SIRT7 modulates the stability and activity of the renal K-Cl cotransporter KCC4 through deacetylation.
Open access · hybridAbstract read
In one paragraph
Article in EMBO reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- A review of the sirtuins family: pivotal regulators and emerging therapeutic targets in renal fibrosis.Renal failure · 2026Review
- Exploring the Role of the SLC12A Cation-Coupled Chloride Cotransporters in the Cardiovascular System.Cells · 2026Review
- Sirtuins and Resveratrol in Cardiorenal Diseases: A Narrative Review of Mechanisms and Therapeutic Potential.Nutrients · 2025Review
- Sirtuins in kidney health and disease.Nature reviews. Nephrology · 2024Review
- Molecular Challenges and Opportunities in Climate Change-Induced Kidney Diseases.Biomolecules · 2024Review
- Sirtuins in kidney diseases: potential mechanism and therapeutic targets.Cell communication and signaling : CCS · 2024Review
- SIRT7: the seventh key to unlocking the mystery of aging.Physiological reviews · 2024Review
- Review
- Arterial Blood Pressure, Neuronal Excitability, Mineral Metabolism and Cell Volume Regulation Mechanisms Revealed byMembranes · 2022Article
- Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury.International journal of molecular sciences · 2022Article
- SIRT7 modulates the stability and activity of the renal K-Cl cotransporter KCC4 through deacetylation.EMBO reports · 2021Article
- The biogenesis of potassium transporters: implications of disease-associated mutations.Critical reviews in biochemistry and molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 6 institutions in 3 countries.
Lilia G NoriegaDepartment of Nutrition Physiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0003-2156-9872
Zesergio MeloDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0002-6702-204X
Renuga D RajaramDepartment of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.
Adriana MercadoDepartment of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.ORCID 0000-0002-6881-0160
Armando R TovarDepartment of Nutrition Physiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Laura A Velazquez-VillegasDepartment of Nutrition Physiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
María Castañeda-BuenoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Yazmín Reyes-LópezDepartment of Nutrition Physiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Dongryeol RyuLaboratory of Integrative and Systems Physiology (LISP), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Lorena Rojas-VegaDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
German Magaña-AvilaDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Adriana M López-BarradasDepartment of Nutrition Physiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Mariana Sánchez-HernándezDepartment of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Anne DebonnevilleDepartment of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.
Alain DoucetCentre de Recherche des Cordeliers, INSERM, Sorbonne Universités, USPC, Université Paris Descartes, Université Paris Diderot, Physiologie Rénale et Tubulopathies, CNRS ERL 8228, Paris, France.
Lydie ChevalCentre de Recherche des Cordeliers, INSERM, Sorbonne Universités, USPC, Université Paris Descartes, Université Paris Diderot, Physiologie Rénale et Tubulopathies, CNRS ERL 8228, Paris, France.
Nimbe TorresDepartment of Nutrition Physiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Johan AuwerxLaboratory of Integrative and Systems Physiology (LISP), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID 0000-0002-5065-5393
Olivier StaubDepartment of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.
Gerardo GambaDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0002-4378-9043
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXUniversity of Lausanne · CHCentre National de la Recherche Scientifique · FRÉcole Polytechnique Fédérale de Lausanne · CHInstituto Nacional de Cardiología · MXMexican Social Security Institute · MX
Funding
Swiss National Science Foundation 310030_189171Swiss National Science Foundation 31003A-140780
Abstract
SIRT7 is a NAD
Indexed as
SirtuinsSymportersAcetylationAnimalsHEK293 CellsHumansK Cl- CotransportersKidneyMiceK Cl- CotransportersSIRT7 protein, humanSirt7 protein, mouseSirtuinsSLC12A7 protein, humanSymporterskidney tubulerenal tubular acidosissirtuins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.