Evidence map›Paper›PMID 33749340›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

A Correlation Between Monocyte to Lymphocyte Ratio and Long-Term Prognosis in Patients With Coronary Artery Disease After PCI.

Feng-Hua Song, Ying-Ying Zheng, Jun-Nan Tang, Wei Wang, Qian-Qian Guo, Jian-Chao Zhang, Yan Bai, Kai Wang, Meng-Die Cheng, Li-Zhu Jiang and 7 more

Abstract read
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Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Feng-Hua SongDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0000-0001-6006-4928
Ying-Ying ZhengDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0000-0003-0003-4270
Jun-Nan TangDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wei WangHenan Medical Association, Zhengzhou, China.
Qian-Qian GuoDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jian-Chao ZhangDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yan BaiDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kai WangDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Meng-Die ChengDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Li-Zhu JiangDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ru-Jie ZhengDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lei FanDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhi-Yu LiuDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xin-Ya DaiDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zeng-Lei ZhangDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiao-Ting YueDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jin-Ying ZhangDepartment of Cardiology, 12636First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monocyte to lymphocyte ratio (MLR) has been confirmed as a novel marker of poor prognosis in patients with coronary heart disease (CAD). However, the prognosis value of MLR for patients with CAD after percutaneous coronary intervention (PCI) needs further studies. In present study, we aimed to investigate the correlation between MLR and long-term prognosis in patients with CAD after PCI. A total of 3,461 patients with CAD after PCI at the First Affiliated Hospital of Zhengzhou University were included in the analysis. According to the cutoff value of MLR, all of the patients were divided into 2 groups: the low-MLR group (<0.34, n = 2338) and the high-MLR group (≥0.34, n = 1123). Kaplan-Meier curve was performed to compare the long-term outcome. Multivariate COX regression analysis was used to assess the independent predictors for all-cause mortality, cardiac mortality and MACCEs. Multivariate COX regression analysis showed that the high MLR group had significantly increased all-cause mortality (ACM) [hazard ratio (HR) = 1.366, 95% confidence interval (CI): 1.366-3.650, p = 0.001] and cardiac mortality (CM) (HR = 2.379, 95%CI: 1.611-3,511, p < 0.001) compared to the low MLR group. And high MLR was also found to be highly associated with major adverse cardiovascular and cerebrovascular events (MACCEs) (HR = 1.227, 95%CI: 1.003-1.500, p = 0.047) in patients with CAD undergoing PCI. MLR was an independent predictor of ACM, CM and MACCEs in CAD patients who underwent PCI.

Indexed as

Coronary Artery DiseaseFemaleFollow-Up StudiesHumansLymphocytesMaleMiddle AgedMonocytesPercutaneous Coronary InterventionPrognosiscoronary artery diseaselong-term prognosismonocyte to lymphocyte ratiopercutaneous coronary intervention

Identifiers

PMID33749340
PMCPMC7989235

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.