Evidence map›Paper›PMID 33749309›Full record

ArticleJournal of the American Heart Association2021

Small Left Ventricle and Clinical Outcomes After Transcatheter Aortic Valve Replacement.

Tetsuya Saito, Taku Inohara, Nobuhiro Yoshijima, Fumiaki Yashima, Hikaru Tsuruta, Hideyuki Shimizu, Keiichi Fukuda, Toru Naganuma, Kazuki Mizutani, Masahiro Yamawaki and 9 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 1 country.

Tetsuya SaitoDepartment of Cardiology Keio University School of Medicine Tokyo Japan.
Taku InoharaDepartment of Cardiology Keio University School of Medicine Tokyo Japan.
Nobuhiro YoshijimaDepartment of Cardiology Keio University School of Medicine Tokyo Japan.
Fumiaki YashimaDepartment of Cardiology Saiseikai Utsunomiya Hospital Tochigi Japan.
Hikaru TsurutaDepartment of Cardiology Keio University School of Medicine Tokyo Japan.
Hideyuki ShimizuDepartment of Cardiovascular Surgery Keio University School of Medicine Tokyo Japan.
Keiichi FukudaDepartment of Cardiology Keio University School of Medicine Tokyo Japan.
Toru NaganumaDepartment of Cardiology New Tokyo Hospital Matsudo Japan.
Kazuki MizutaniDepartment of Cardiology Osaka City General Hospital Osaka Japan.
Masahiro YamawakiDepartment of Cardiology Saiseikai Yokohama-City Eastern Hospital Yokohama Japan.
Norio TadaDepartment of Cardiology Sendai Kousei Hospital Sendai Japan.
Futoshi YamanakaDepartment of Cardiology Shonan Kamakura General Hospital Kamakura Japan.
Shinichi ShiraiDepartment of Cardiology Kokura Memorial Hospital Kokura Japan.
Minoru TabataDepartment of Cardiovascular Surgery Tokyo Bay Urayasu-Ichikawa Medical Center Chiba Japan.
Hiroshi UenoDepartment of Cardiology Toyama University Hospital Toyama Japan.
Kensuke TakagiDepartment of Cardiology Ogaki Municipal Hospital Gifu Japan.
Yusuke WatanabeDepartment of Cardiology Teikyo University School of Medicine Tokyo Japan.
Masanori YamamotoDepartment of Cardiology Toyohashi Heart Center Toyohashi Japan.
Kentaro HayashidaDepartment of Cardiology Keio University School of Medicine Tokyo Japan.
Keio University · JPKokura Memorial Hospital · JPNew Tokyo Hospital · JPOgaki Municipal Hospital · JPOsaka City General Hospital · JPSaiseikai Utsunomiya hospital · JPSaiseikai Yokohama Eastern Hospital · JPSendai Kousei Hospital · JPShonan Kamakura General Hospital · JPTeikyo University · JPToyama University Hospital · JPToyohashi Heart Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In patients undergoing transcatheter aortic valve replacement (TAVR), those with small left ventricle (LV) may have an increased risk of poor outcomes, because small LV is associated with low-flow (LF), left ventricular hypertrophy. However, the impact of small LV on patients undergoing TAVR remains unknown. Methods and Results We examined 2584 patients who underwent TAVR between October 2013 and May 2017 using data from the Japanese multicenter registry. On the basis of the American Society of Echocardiography guidelines, small LV was defined as left ventricular end-diastolic dimension <42.0 mm for men or <37.8 mm for women. The 2-year clinical outcomes were compared between patients with and without small LV using multivariable Cox regression analyses and propensity score matching. Subgroup analyses by LF, left ventricular hypertrophy were performed. Of 2584 patients who underwent TAVR, 466 (18.0%) had small LV. Patients with small LV had smaller body size and less comorbidity, and were more likely to have LF status compared with those without. Small LV was associated with a higher 2-year all-cause (20.8% versus 14.3%; adjusted hazard ratio [HR],1.58 [95% CI, 1.20-2.09];

Indexed as

RegistriesAged, 80 and overAortic ValveAortic Valve StenosisDiastoleEchocardiographyFemaleFollow-Up StudiesHeart VentriclesHumansMaleOrgan SizePropensity ScoreRetrospective StudiesRisk FactorsSeverity of Illness Indexheart failureleft ventricular end‐diastolic dimensionleft ventricular hypertrophypropensity score matchingtranscatheter aortic valve replacement

Identifiers

PMID33749309
PMCPMC8174314
OpenAlexW3136164129

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.