Evidence map›Paper›PMID 33749238›Full record

ArticleBiochemistry2021

Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of

Vijay Kumar, Snigdha A Mathure, Mijoon Lee, Jacob Boorman, Ximin Zeng, Jun Lin, Dusan Hesek, Elena Lastochkin, Shahriar Mobashery, Focco van den Akker

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Multi-Omics ofMicroorganisms · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Vijay KumarDepartment of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Snigdha A MathureDepartment of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Mijoon LeeDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0001-7432-0427
Jacob BoormanDepartment of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Ximin ZengDepartment of Animal Science, University of Tennessee, Knoxville, Tennessee 37996, United States.
Jun LinDepartment of Animal Science, University of Tennessee, Knoxville, Tennessee 37996, United States.
Dusan HesekDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Elena LastochkinDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Shahriar MobasheryDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0002-7695-7883
Focco van den AkkerDepartment of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0001-9210-3565
Case Western Reserve University · USUniversity of Notre Dame · USUniversity of Tennessee at Knoxville · US

Funding

Cell-Wall Recycling and Nexus to Antibiotic ResistanceR35GM131685 · NIGMS · UNIVERSITY OF NOTRE DAME · PI MOBASHERY, SHAHRIAR · 2019 to 2023
$1.9M
Small molecule inhibitors of lytic transglycosylase to potentiate beta-lactam antibioticsR21AI148875 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI VAN DEN AKKER, FOCCO · 2020 to 2021
$451k
NIAID NIH HHS R21 AI148875NIGMS NIH HHS R35 GM131685
6 · The paper itself

Abstract

The soluble lytic transglycosylase Cj0843c from

Indexed as

Campylobacter jejuniBacterial ProteinsCatalytic DomainCrystallography, X-RayGlycosyltransferasesModels, MolecularMolecular Dynamics SimulationMutagenesis, Site-DirectedPeptidoglycanProtein ConformationSubstrate SpecificityBacterial ProteinsGlycosyltransferasesPeptidoglycan

Identifiers

PMID33749238
PMCPMC9067259
OpenAlexW3138895052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.