Evidence map›Paper›PMID 33749070›Full record

ArticleJournal of cellular and molecular medicine2021

Dysregulation of LINC00470 and METTL3 promotes chemoresistance and suppresses autophagy of chronic myelocytic leukaemia cells.

Xun Lai, Jia Wei, Xue-Zhong Gu, Xiang-Mei Yao, Di-Si Zhang, Feng Li, Yun-Yan Sun

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
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  6. Methyltransferase-like 3-mediated RNA NFrontiers in immunology · 2025
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  7. Article
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  9. Autophagy: a critical mechanism of NCell death & disease · 2024
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  12. NCellular and molecular life sciences : CMLS · 2024
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xun LaiDepartment of Hematology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, China.
Jia WeiDepartment of Hematology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, China.
Xue-Zhong GuDepartment of Hematology, The First People's Hospital of Yunnan Province, Kunming, China.
Xiang-Mei YaoDepartment of Hematology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, China.
Di-Si ZhangDepartment of Hematology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, China.
Feng LiDepartment of Hematology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, China.
Yun-Yan SunDepartment of Hematology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, China.ORCID 0000-0002-9866-2939
Kunming Medical University · CNFirst People's Hospital of Yunnan Province · CN

Funding

Yunnan Provincial Department of Science and Technology 2017FE468 (-105)Yunnan Provincial Department of Science and Technology 2018FE001(-113)
6 · The paper itself

Abstract

Cytoplasmic lncRNAs have been found to directly interact with target mRNAs and regulate their stability. In this study, we aimed to study the molecular mechanism underlying the function of m

Indexed as

AutophagyDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticAnimalsAntineoplastic AgentsApoptosisBiomarkers, TumorCell ProliferationHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleMethyltransferasesMiceMice, Inbred BALB CMice, NudePTEN PhosphohydrolaseAntineoplastic AgentsBiomarkers, TumorMethyltransferasesMETTL3 protein, humanPTEN PhosphohydrolasePTEN protein, humanRNA, Long NoncodingAKTautophagychemoresistanceChronic myelocytic leukaemiaLINC00470METTL3PTEN

Identifiers

PMID33749070
PMCPMC8093980
OpenAlexW3136154348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.