Evidence map›Paper›PMID 33748880›Full record

ArticleJournal of cancer research and clinical oncology2021

Self-medication with herbal medicine and breast cancer survival: a prospective monocentric study.

Wala Ben Kridis, Ahmed Mnif, Souhir Khmiri, Nabil Toumi, Afef Khanfir

Abstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The Canadian journal of hospital pharmacy · 2024
    Article
  4. Article
  5. Chemopreventive Effects ofCurrent issues in molecular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wala Ben KridisDepartment of Medical Oncology, Habib Bourguiba Hospital University of Sfax, 3029, Sfax, Tunisia. walabenkridis@yahoo.fr.ORCID http://orcid.org/0000-0002-4956-9551
Ahmed MnifDepartment of Medical Oncology, Habib Bourguiba Hospital University of Sfax, 3029, Sfax, Tunisia.
Souhir KhmiriDepartment of Medical Oncology, Habib Bourguiba Hospital University of Sfax, 3029, Sfax, Tunisia.
Nabil ToumiDepartment of Medical Oncology, Habib Bourguiba Hospital University of Sfax, 3029, Sfax, Tunisia.
Afef KhanfirDepartment of Medical Oncology, Habib Bourguiba Hospital University of Sfax, 3029, Sfax, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe use of complementary and alternative medicine (CAM) is common among breast cancer patients, but less is known about whether CAM influences breast cancer survival. The primary aim of this study was to determine the impact of self-use of herbs on the overall survival.

methodsThis was a prospective study including 110 patients with breast cancer. All patients were questioned about the concept of taking herbs. We analyzed the demographic data and the overall survival.

resultsThe average age was 51 years (30-80 years old). 37 had metastatic disease (33.6%). 48 patients had taken plants (43.6%). 19 patients consumed Graviola (39.6%) and 29 Alenda (60.4%). Overall survival at 3 years and at 5 years were, respectively, 96.2% and 82.4% in the absence of plant consumption versus 78.5% and 78.5% in case of plant consumption (p = 0.015).

conclusionThis study concluded that self-medication with Graviola or Alenda may be associated with an increase of death risk in patients with breast cancer. Further studies are needed to confirm these results.

Indexed as

AnnonaEphedraPlants, MedicinalAdultAgedAged, 80 and overBreast NeoplasmsComplementary TherapiesFemaleHumansMiddle AgedPhytotherapyProspective StudiesSelf MedicationAlternative medicineBreast cancerComplementary medicinesInteractionNeoplasmPhytotherapySurvival

Identifiers

PMID33748880
PMCPMC11802091

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.