Evidence map›Paper›PMID 33748808›Full record

ArticleJournal of the American College of Emergency Physicians open2021

COVID-19: A new barrier to treatment for opioid use disorder in the emergency department.

Warren Grunvald, Ramsey Herrington, Roz King, Miles Lamberson, Scott Mackey, Sanchit Maruti, Richard Rawson, Daniel Wolfson

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The relationship between COVID-19 and opioid-related emergency department visits in Alberta, Canada: an interrupted time series analysis.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. COVID-19: A new barrier to treatment for opioid use disorder in the emergency department.Journal of the American College of Emergency Physicians open · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Warren GrunvaldUniversity of Vermont Larner College of Medicine Burlington Vermont USA.
Ramsey HerringtonDivision of Emergency Medicine, University of Vermont Larner College of Medicine Burlington Vermont USA.
Roz KingDivision of Emergency Medicine, University of Vermont Larner College of Medicine Burlington Vermont USA.
Miles LambersonDivision of Emergency Medicine, University of Vermont Larner College of Medicine Burlington Vermont USA.
Scott MackeyDivision of Psychiatry, University of Vermont Larner College of Medicine Burlington Vermont USA.
Sanchit MarutiDivision of Psychiatry, University of Vermont Larner College of Medicine Burlington Vermont USA.
Richard RawsonDivision of Psychiatry, University of Vermont Larner College of Medicine Burlington Vermont USA.
Daniel WolfsonDivision of Emergency Medicine, University of Vermont Larner College of Medicine Burlington Vermont USA.

Funding

Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI KHADANGA, SHERRIE · 2013 to 2022
$21.3M
Effectiveness of Bridge Clinic Following Emergency Department-Initiated Intervention for Opioid Use DisorderR21DA049859 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI MACKEY, SCOTT, MARUTI, SANCHIT · 2019 to 2020
$425k
NIDA NIH HHS R21 DA049859NIGMS NIH HHS P20 GM103644
6 · The paper itself

Abstract

objectiveStart Treatment and Recover (STAR) is an emergency department (ED) program that expands access to medication for opioid use disorder by identifying patients with opioid use disorder and offering ED-initiated buprenorphine/naloxone and rapid access to outpatient treatment. We sought to determine the impacts of the coronavirus disease 2019 pandemic on STAR and the patients with opioid use disorder it serves.

methodsWe conducted a retrospective review of records comparing 2 periods: pre-pandemic (February 1, 2019-February 29, 2020) and pandemic (March 1, 2020-May 31, 2020). Variables evaluated included the number of STAR enrollments, ED census, percentage of census screening positive for opioid use disorder, number and percentage of ED overdose visits, and overdose fatalities by month. All analyses were conducted using 2-sample

resultsComparing the pre-pandemic to the pandemic period, the mean monthly ED visits decreased from 5126.9 to 3306.7 (difference = -1820.3; 95% CI, -3406.3 to -234.2), STAR mean monthly enrollments decreased from 9.7 to 1.3 (difference = -8.4; 95% CI, -12.8 to -4.0), and statewide monthly opioid-related fatalities increased from 9.4 to 15.3 (difference = 5.9; 95% CI, 0.8 to 11.1). However, the percentage of individuals who presented to the ED with opioid use disorder or overdose remained unchanged.

conclusionAlthough overall ED visits declined during the pandemic period, the percentage of patients presenting with opioid use disorder or overdose remained constant, yet there was a dramatic decline in enrollment in ED-initiated medication for opioid use disorder and an increase in statewide monthly opioid-related fatalities. Strategies to maintain medication for opioid use disorder treatment options must be implemented for this vulnerable population during the ongoing pandemic.

Indexed as

buprenorphine naloxone drug combinationCOVID‐19emergency departmentsopioid medication assisted treatmentopioid‐related disordersopioid use disordervulnerable populations

Identifiers

PMID33748808
PMCPMC7967916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.