Evidence map›Paper›PMID 33748774›Full record

ArticleCurrent tissue microenvironment reports2020

Pericytes in Vascular Development.

Laura Beth Payne, Maruf Hoque, Clifton Houk, Jordan Darden, John C Chappell

Open access · greenAbstract read
In one paragraph

Article in Current tissue microenvironment reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

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  18. Glioma Pericytes Promote Angiogenesis by Producing Periostin.Cellular and molecular neurobiology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Laura Beth PayneCenter for Heart and Reparative Medicine Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke, VA 24016, USA.
Maruf HoqueCenter for Heart and Reparative Medicine Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke, VA 24016, USA.
Clifton HoukVirginia Tech Carilion School of Medicine, Roanoke, VA, 24016, USA.
Jordan DardenCenter for Heart and Reparative Medicine Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke, VA 24016, USA.
John C ChappellCenter for Heart and Reparative Medicine Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke, VA 24016, USA.ORCID 0000-0002-0427-5170
Carilion Roanoke Memorial Hospital · USCarilion Clinic · USCommunity Options (United States) · US

Funding

Vascular Basement Membrane Composition Regulates Pericyte Investment in Developing Blood VesselsR01HL146596 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CHAPPELL, JOHN CHRISTOPHER · 2019 to 2022
$1.6M
NHLBI NIH HHS R01 HL146596
6 · The paper itself

Abstract

purpose of reviewPericytes are essential components of capillaries in many tissues and organs, contributing to vessel stability and integrity, with additional contributions to microvascular function still being discovered. We review current and foundational studies identifying pericyte differentiation mechanics and their roles in the earliest stages of vessel formation. RECENT

findingsRecent advances in pericyte-focused tools and models have illuminated critical aspects of pericyte biology including their roles in vascular development.Pericytes likely collaborate with endothelial cells undergoing vasculogenesis, initiating direct interactions during sprouting and intussusceptive angiogenesis. Pericytes also provide important regulation of vascular growth including mechanisms underlying vessel pruning, rarefaction, and subsequent regrowth.

Indexed as

angiogenesisendothelial cellmural cell differentiationpericytevascular developmentvasculogenesis

Identifiers

PMID33748774
PMCPMC7967288
OpenAlexW3039877187

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.