Evidence map›Paper›PMID 33748739›Full record

ReviewInternational Journal of Cardiology. Hypertension2021

The effect of remote ischaemic conditioning on blood pressure response: A systematic review and meta-analysis.

Biggie Baffour-Awuah, Gudrun Dieberg, Melissa J Pearson, Neil A Smart

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International Journal of Cardiology. Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05971407 (The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05971407 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults

TypeinterventionalSponsorUniversity of NottinghamRan2022 to 2024Enrolled60ConditionsHypertension, Vascular DiseasesArmsRemote Ischaemic Preconditioning, Sham Remote Ischaemic Preconditioning
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Remote ischemic conditioning for stroke: A critical systematic review.International journal of stroke : official journal of the International Stroke Society · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Biggie Baffour-AwuahClinical Exercise Physiology, School of Science and Technology, Faculty of Science, Agriculture, Business and Law, University of New England, Armidale, NSW, 2351, Australia.
Gudrun DiebergBiomedical Sciences, School of Science and Technology, Faculty of Science, Agriculture, Business and Law, University of New England, Armidale, NSW, 2351, Australia.
Melissa J PearsonClinical Exercise Physiology, School of Science and Technology, Faculty of Science, Agriculture, Business and Law, University of New England, Armidale, NSW, 2351, Australia.
Neil A SmartClinical Exercise Physiology, School of Science and Technology, Faculty of Science, Agriculture, Business and Law, University of New England, Armidale, NSW, 2351, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious work has evaluated the effect of remote ischaemic conditioning (RIC) in a number of clinical conditions (e.g. cardiac surgery and acute kidney injury), but only one analysis has examined blood pressure (BP) changes. While individual studies have reported the effects of acute bouts and repeated RIC exposure on resting BP, efficacy is equivocal. We conducted a systematic review and meta-analysis to evaluate the effects of acute and repeat RIC on BP.

methodsA systematic search was performed using PubMed, Web of Science, EMBASE, and Cochrane Library of Controlled Trials up until October 31, 2020. Additionally, manual searches of reference lists were performed. Studies that compared BP responses after exposing participants to either an acute bout or repeated cycles of RIC with a minimum one-week intervention period were considered.

resultsEighteen studies were included in this systematic review, ten examined acute effects while eight investigated repeat effects of RIC. Mean differences (MD) for outcome measures from acute RIC studies were: systolic BP 0.18 mmHg (95%CI -0.95, 1.31;

conclusionsOur data suggests repeated, but not acute, RIC produced clinically meaningful reductions in diastolic BP and MAP.

Indexed as

Acute remote ischaemic conditioningBlood pressureBP, blood pressureCABG, coronary artery bypass graftingCI, confidence intervalHR, heart rateMD, mean differenceRepeat remote ischaemic conditioningRICRIC, Remote ischaemic conditioningSD, standard deviationT2DM, type 2 diabetes mellitusVEGF, vascular endothelial growth factor

Identifiers

PMID33748739
PMCPMC7972960

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.