Evidence map›Paper›PMID 33748644›Full record

ArticleJB & JS open access

Preoperative Risk Prediction Models for Short-Term Revision and Death After Total Hip Arthroplasty: Data from the Finnish Arthroplasty Register.

Mikko S Venäläinen, Valtteri J Panula, Riku Klén, Jaason J Haapakoski, Antti P Eskelinen, Mikko J Manninen, Jukka S Kettunen, Ari-Pekka Puhto, Anna I Vasara, Keijo T Mäkelä and 1 more

Open access · goldAbstract read
In one paragraph

Article in JB & JS open access. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Mikko S VenäläinenTurku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.ORCID 0000-0003-1777-4259
Valtteri J PanulaDepartment of Orthopaedics and Traumatology, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0001-6638-3188
Riku KlénTurku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.ORCID 0000-0002-0982-8360
Jaason J HaapakoskiNational Institute for Health and Welfare, Helsinki, Finland.ORCID 0000-0001-5145-3956
Antti P EskelinenCoxa Hospital for Joint Replacement, Tampere, Finland.ORCID 0000-0003-0302-0253
Mikko J ManninenOrton Hospital, Helsinki, Finland.ORCID 0000-0002-9681-8821
Jukka S KettunenDepartment of Orthopaedics and Traumatology, Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0002-7198-2772
Ari-Pekka PuhtoDivision of Operative Care, Department of Orthopaedic and Trauma Surgery, Oulu University Hospital, Oulu, Finland.ORCID 0000-0002-5006-4876
Anna I VasaraHelsinki University Hospital, Helsinki, Finland.ORCID 0000-0001-6706-1674
Keijo T MäkeläDepartment of Orthopaedics and Traumatology, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0002-4115-1767
Laura L EloTurku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.ORCID 0000-0001-5648-4532
Åbo Akademi University · FIUniversity of Turku · FICoxa Hospital · FIFinnish Institute for Health and Welfare · FIHelsinki University Hospital · FIInvalidisäätiö · FIKuopio University Hospital · FIOulu University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because of the increasing number of total hip arthroplasties (THAs), even a small proportion of complications after the operation can lead to substantial individual difficulties and health-care costs. The aim of this study was to develop simple-to-use risk prediction models to assess the risk of the most common reasons for implant failure to facilitate clinical decision-making and to ensure long-term survival of primary THAs.

methodsWe analyzed patient and surgical data reported to the Finnish Arthroplasty Register (FAR) on 25,919 primary THAs performed in Finland between May 2014 and January 2018. For the most frequent adverse outcomes after primary THA, we developed multivariable Lasso regression models based on the data of the randomly selected training cohort (two-thirds of the data). The performances of all models were validated using the remaining, independent test set consisting of 8,640 primary THAs (one-third of the data) not used for building the models.

resultsThe most common outcomes within 6 months after the primary THA were revision operations due to periprosthetic joint infection (1.1%), dislocation (0.7%), or periprosthetic fracture (0.5%), and death (0.7%). For each of these outcomes, Lasso regression identified subsets of variables required for accurate risk predictions. The highest discrimination performance, in terms of area under the receiver operating characteristic curve (AUROC), was observed for death (0.84), whereas the performance was lower for revisions due to periprosthetic joint infection (0.68), dislocation (0.64), or periprosthetic fracture (0.65).

conclusionsBased on the small number of preoperative characteristics of the patient and modifiable surgical parameters, the developed risk prediction models can be easily used to assess the risk of revision or death. All developed models hold the potential to aid clinical decision-making, ultimately leading to improved clinical outcomes. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Identifiers

PMID33748644
PMCPMC7963508
OpenAlexW3123097840

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.