Evidence map›Paper›PMID 33748616›Full record

ArticleACS omega2021

Maltotriose-Chlorin e6 Conjugate Linked

Atsushi Narumi, Rioko Rachi, Hiromi Yamazaki, Seigou Kawaguchi, Moriya Kikuchi, Hiroyuki Konno, Tomohiro Osaki, Yoshiharu Okamoto, Xiande Shen, Toyoji Kakuchi and 4 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Atsushi NarumiGraduate School of Organic Materials Science, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510, Japan.
Rioko RachiGraduate School of Organic Materials Science, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510, Japan.
Hiromi YamazakiGraduate School of Organic Materials Science, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510, Japan.
Seigou KawaguchiGraduate School of Organic Materials Science, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510, Japan.
Moriya KikuchiFaculty of Engineering, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510, Japan.
Hiroyuki KonnoGraduate School of Science and Engineering, Yamagata University, Yonezawa, Yamagata 992-8510, Japan.
Tomohiro OsakiJoint Department of Veterinary Clinical Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
Yoshiharu OkamotoJoint Department of Veterinary Clinical Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
Xiande ShenResearch Center for Polymer Materials, School of Materials Science and Engineering, Changchun University of Science and Technology, Weixing Road 7989, Jilin 130022, China.
Toyoji KakuchiResearch Center for Polymer Materials, School of Materials Science and Engineering, Changchun University of Science and Technology, Weixing Road 7989, Jilin 130022, China.
Hiromi KataokaDepartment of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan.
Akihiro NomotoDepartment of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan.
Tomokazu YoshimuraKYOUSEI Science Center for Life and Nature, Nara Women's University, Kitauoyahigashi-machi, Nara 630-8506, Japan.
Shigenobu YanoKYOUSEI Science Center for Life and Nature, Nara Women's University, Kitauoyahigashi-machi, Nara 630-8506, Japan.
Yamagata University · JPChangchun University of Science and Technology · CNNara Women's University · JPTottori University · JPNagoya City University · JPOsaka Prefecture University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycoconjugated chlorins represent a promising class of compounds that meet the requirements for the third-generation photosensitizer (PS) for photodynamic therapy (PDT). We have focused on the use of glucose (Glc) to improve the performance of the PS based on the Warburg effect-a phenomenon where tumors consume higher Glc levels than normal cells. However, as a matter of fact, Glc-conjugation has a poor efficacy in hydrophilic modification; thus, the resultant PS is not suitable for intravenous injection. In this study, a Glc-based oligosaccharide, such as maltotriose (Mal

Identifiers

PMID33748616
PMCPMC7970547
OpenAlexW3134413873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.