Evidence map›Paper›PMID 33748539›Full record

ArticleNeurobiology of sleep and circadian rhythms2021

Night shift schedule alters endogenous regulation of circulating cytokines.

Peter Y Liu, Michael R Irwin, James M Krueger, Shobhan Gaddameedhi, Hans P A Van Dongen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of sleep and circadian rhythms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Sleep, testosterone and cortisol balance, and ageing men.Reviews in endocrine & metabolic disorders · 2022
    Review
  10. Time to Sleep?-A Review of the Impact of the COVID-19 Pandemic on Sleep and Mental Health.International journal of environmental research and public health · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Sleep and Circadian Regulation of Cortisol: A Short Review.Current opinion in endocrine and metabolic research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Peter Y LiuDivision of Endocrinology, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
Michael R IrwinDavid Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA, 90095, USA.
James M KruegerDepartment of Integrative Physiology and Neuroscience, Washington State University, Spokane, WA, 99202, USA.
Shobhan GaddameedhiDepartment of Biological Sciences, North Carolina State University, Raleigh, NC, 27606, USA.
Hans P A Van DongenSleep and Performance Research Center, Washington State University, Spokane, WA, 99202, USA.
Washington State University Spokane · USNorth Carolina State University · USUniversity of California, Los Angeles · USUniversity of Southern California · US

Funding

Hormonal Mechanisms of Sleep RestrictionR01HL124211 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI LIU, PETER YIWEN · 2014 to 2019
$2.1M
DNA Repair Mechanisms and Circadian Clock Disruption in the CorneaR01ES030113 · NIEHS · WASHINGTON STATE UNIVERSITY · PI GADDAMEEDHI, SHOBHAN · 2020 to 2025
$2.1M
Mentorship in the Endocrinology of SleepK24HL138632 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI LIU, PETER YIWEN · 2018 to 2022
$598k
NHLBI NIH HHS K24 HL138632NHLBI NIH HHS R01 HL124211NIEHS NIH HHS R01 ES030113
6 · The paper itself

Abstract

Night shift work is a risk factor for viral infection, suggesting that night shift schedules compromise host defense mechanisms. Prior studies have investigated changes in the temporal profiles of circulating cytokines important for priming and restraining the immune response to infectious challenges from night shift work, but not by way of a 24-h constant routine of continuous wakefulness devoid of behavioral or environmental influences. Hence the true

Indexed as

COVID-19Cytokine stormInfectious diseaseInflammationNight workTemporal regulation

Identifiers

PMID33748539
PMCPMC7970107
OpenAlexW3134054323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.