Evidence map›Paper›PMID 33748270›Full record

ArticleBioMed research international2021

DUOX2 As a Potential Prognostic Marker which Promotes Cell Motility and Proliferation in Pancreatic Cancer.

Meng Cao, Peng-Bo Zhang, Peng-Fei Wu, Qun Chen, Wan-Li Ge, Guo-Dong Shi, Jie Yin, Bao-Bao Cai, Shou-Ji Cao, Yi Miao and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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  5. Overexpression ofGland surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Meng CaoPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.ORCID https://orcid.org/0000-0001-9166-2824
Peng-Bo ZhangPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Peng-Fei WuPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Qun ChenPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Wan-Li GePancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Guo-Dong ShiPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jie YinPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Bao-Bao CaiPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Shou-Ji CaoPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Yi MiaoPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.ORCID https://orcid.org/0000-0003-2542-8663
Kui-Rong JiangPancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-2849-5450
Jiangsu Province Hospital · CNNanjing Drum Tower Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DUOX2 has been reported to highly express in several types of cancers. However, the prognostic significance and the biological function of DUOX2 expression with pancreatic cancer (PC) still remain unclear. The present study is aimed at investigating whether DUOX2 could act as a novel biomarker of prognosis and evaluating its effect on PC cell progression. The mRNA and protein expression of DUOX2 in PC cells and tissues were assessed by quantitative real-time PCR (RT-qPCR) and immunohistochemistry. The effect of DUOX2 expression on PC cell motility and proliferation was evaluated

Indexed as

Cell MovementCell ProliferationGene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticBiomarkers, TumorCell Line, TumorDual OxidasesFemaleHumansMaleNeoplasm ProteinsPancreatic NeoplasmsPrognosisBiomarkers, TumorDual OxidasesDUOX2 protein, humanNeoplasm Proteins

Identifiers

PMID33748270
PMCPMC7943273
OpenAlexW3133794564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.