Evidence map›Paper›PMID 33748113›Full record

ArticleFrontiers in cell and developmental biology2021

METTL3 Regulates Ossification of the Posterior Longitudinal Ligament via the lncRNA XIST/miR-302a-3p/USP8 Axis.

Xiaoqiu Yuan, Lei Shi, Yongfei Guo, Jingchuan Sun, Jinhao Miao, Jiangang Shi, Yu Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
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  4. Potential regulatory role of the mActa biochimica et biophysica Sinica · 2025
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  10. Review
  11. Reprogramming tendon healing: a guide to novel molecular tools.Frontiers in bioengineering and biotechnology · 2024
    Review
  12. METTL3-Mediated lncSNHG7 mJournal of clinical medicine · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Novel Insights Into the Multifaceted Functions of RNA nFrontiers in cell and developmental biology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoqiu YuanSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Lei ShiSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Yongfei GuoSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Jingchuan SunSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Jinhao MiaoSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Jiangang ShiSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Yu ChenSpine Center, Department of Orthopaedics, Changzheng Hospital, Naval Medical University, Shanghai, China.
Second Military Medical University · CNShanghai Changzheng Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of ossification of the posterior longitudinal ligament (OPLL) is increasing, and currently there is no effective medical treatment for OPLL. Methyltransferase like 3 (METTL3), one of the components of the

Indexed as

long non-coding RNAm6A methylationmethyltransferase like 3miR-302a-3possification of the posterior longitudinal ligamentX-inactive specific transcript

Identifiers

PMID33748113
PMCPMC7973222
OpenAlexW3134151728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.