Evidence map›Paper›PMID 33748051›Full record

ArticleFrontiers in pediatrics2021

Case Report: Neonatal Varicella Acquired From Maternal Zoster.

Jeffrey W Lai, Timothy Ford, Sarah Cherian, Anita J Campbell, Christopher C Blyth

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jeffrey W LaiSchool of Medicine, The University of Western Australia, Crawley, WA, Australia.
Timothy FordDepartment of Infectious Diseases, Perth Children's Hospital, Nedlands, WA, Australia.
Sarah CherianDepartment of Infectious Diseases, Perth Children's Hospital, Nedlands, WA, Australia.
Anita J CampbellDepartment of Infectious Diseases, Perth Children's Hospital, Nedlands, WA, Australia.
Christopher C BlythSchool of Medicine, The University of Western Australia, Crawley, WA, Australia.
Perth Children's HospitalPrincess Margaret Hospital for Children · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of neonatal varicella has decreased dramatically since the introduction of the varicella vaccination. Although the varicella zoster virus is often associated with a mild infection, it may cause severe morbidity and mortality, particularly in the neonatal period and immunocompromised hosts. We report a case of neonatal varicella acquired from maternal zoster in a mother on biological immunosuppressive therapy. Following the diagnosis, the baby improved on antiviral therapy without any neurological sequelae. This case highlights the limited published data on neonatal varicella following herpes zoster reactivation to inform practice. This includes the role of varicella zoster immunoglobulin in neonates exposed to maternal zoster, the degree of trans-placental immunity and optimum antiviral dosing and duration.

Indexed as

maternal immunosuppressionmaternal zosterneonatal varicellatrans-placental immunityvaricella zoster immune globulin

Identifiers

PMID33748051
PMCPMC7965958
OpenAlexW3134554790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.