Evidence map›Paper›PMID 33747978›Full record

ArticleFrontiers in cellular and infection microbiology2021

Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen,

Carlos Talavera-López, Louisa A Messenger, Michael D Lewis, Matthew Yeo, João Luís Reis-Cunha, Gabriel Machado Matos, Daniella C Bartholomeu, José E Calzada, Azael Saldaña, Juan David Ramírez and 16 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

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  10. Identification of highly conservedEmerging microbes & infections · 2024
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  15. Review
  16. Fifteen Years after the Definition ofLife (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Whole Genome Assembly of a HybridbioRxiv : the preprint server for biology · 2023
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  19. The ElusivePathogens (Basel, Switzerland) · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Carlos Talavera-LópezDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Louisa A MessengerFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Michael D LewisFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Matthew YeoFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
João Luís Reis-CunhaDepartamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Gabriel Machado MatosDepartamento de Biologia Celular, Embriologia e Genética, Universidade Federal Santa Catarina, Florianópolis, Brazil.
Daniella C BartholomeuDepartamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
José E CalzadaDepartamento de Parasitología, Instituto Conmemorativo Gorgas de Estudios de la Salud, Ciudad de Panamá, Panama.
Azael SaldañaDepartamento de Parasitología, Instituto Conmemorativo Gorgas de Estudios de la Salud, Ciudad de Panamá, Panama.
Juan David RamírezGrupo de Investigaciones Microbiológicas-UR (GIMUR), Departamento de Biología, Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.
Felipe GuhlGrupo de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Tropical Parasitology Research Center, Universidad de Los Andes, Bogotá, Colombia.
Sofía Ocaña-MayorgaCentro de Investigación para la Salud en América Latina (CISeAL), Escuela de Ciencias Biológicas, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Jaime A CostalesCentro de Investigación para la Salud en América Latina (CISeAL), Escuela de Ciencias Biológicas, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Rodion GorchakovSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Department of Pediatrics - Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Kathryn JonesSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Department of Pediatrics - Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Melissa S NolanSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Department of Pediatrics - Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Santuza M R TeixeiraDepartamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Hernán José CarrascoLaboratorio de Biología Molecular de Protozoarios, Instituto de Medicina Tropical, Facultad de Medicina, Universidad Central de Venezuela, Caracas, Venezuela.
Maria Elena BottazziSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Department of Pediatrics - Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Peter J HotezSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Department of Pediatrics - Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Kristy O MurraySabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Department of Pediatrics - Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Mario J GrijalvaCentro de Investigación para la Salud en América Latina (CISeAL), Escuela de Ciencias Biológicas, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Barbara BurleighDepartment of Immunology and Infectious Diseases, T.H. Chan School of Public Health, Harvard University, Boston, MA, United States.
Edmundo C GrisardDepartamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal Santa Catarina, Florianópolis, Brazil.
Michael A MilesFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Björn AnderssonDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

Funding

Predictors of cardiomyopathy progression in a Chagas disease cohort in BoliviaR01AI107028 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GILMAN, ROBERT H · 2014 to 2023
$6.6M
NIAID NIH HHS R01 AI107028
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigenic VariationTrypanosoma cruziMultigene FamilySyntenyantigenic variationgenome sequencemicrobial genomicsparasitologypathology of infectious diseasespopulation geneticstropical medicineTrypanosoma cruzi

Identifiers

PMID33747978
PMCPMC7966520

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.