Evidence map›Paper›PMID 33747919›Full record

ArticleFrontiers in oncology2021

Prognostic Relevance of Expression of

Jay Singh, Sarita Kumari, Mohit Arora, Deepak Verma, Jayanth Kumar Palanichamy, Rajive Kumar, Gunjan Sharma, Sameer Bakhshi, Deepam Pushpam, M Shadab Ali and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Therapeutic Significance of NLRP3 Inflammasome in Cancer: Friend or Foe?International journal of molecular sciences · 2024
    Review
  5. Article
  6. Review
  7. The Impact of NLRP3 Activation on Hematopoietic Stem Cell Transplantation.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Jay SinghLaboratory Oncology Unit, Dr. B.R. Ambedkar-Insitute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Sarita KumariLaboratory Oncology Unit, Dr. B.R. Ambedkar-Insitute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Mohit AroraDepartment of Biochemistry, AIIMS, New Delhi, India.
Deepak VermaLaboratory Oncology Unit, Dr. B.R. Ambedkar-Insitute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Jayanth Kumar PalanichamyDepartment of Biochemistry, AIIMS, New Delhi, India.
Rajive KumarDepartment of Pathology, Mahavir Cancer Sansthan, Patna, India.
Gunjan SharmaDepartment of Biochemistry, AIIMS, New Delhi, India.
Sameer BakhshiDepartment of Medical Oncology, AIIMS, New Delhi, India.
Deepam PushpamDepartment of Medical Oncology, AIIMS, New Delhi, India.
M Shadab AliDepartment of Pulmonary Medicine, AIIMS, New Delhi, India.
Amar RanjanLaboratory Oncology Unit, Dr. B.R. Ambedkar-Insitute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Pranay TanwarLaboratory Oncology Unit, Dr. B.R. Ambedkar-Insitute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Shyam S ChauhanDepartment of Biochemistry, AIIMS, New Delhi, India.
Archna SinghDepartment of Biochemistry, AIIMS, New Delhi, India.
Anita ChopraLaboratory Oncology Unit, Dr. B.R. Ambedkar-Insitute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi, India.
All India Institute of Medical Sciences · INAll India Institute of Medical Sciences Bhopal · INDR. B.R.A. Institute Rotary Cancer Hospital · INAll India Institute of Medical Sciences Raipur · INMahavir Cancer Institute and Research Centre · IN

Funding

DBT-Wellcome Trust India Alliance IA/CPHI/17/1/503333
6 · The paper itself

Abstract

Glucocorticoid (GC), such as prednisolone, is an essential component of multidrug chemotherapy regimen for pediatric acute lymphoblastic leukemia (ALL). Resistance to GC in leukemia cells is associated with disease progression and poor prognosis. Despite the extensive use of GC for many years, molecular mechanisms underlying its resistance in ALL have not been fully uncovered. Recent studies have shown a potential role of

Indexed as

B-ALLCASP1EMP1leukemiaNLRP3prednisolone resistance

Identifiers

PMID33747919
PMCPMC7973229
OpenAlexW3134561453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.