Evidence map›Paper›PMID 33747819›Full record

ArticleInternational journal of ophthalmology2021

Real-world outcomes of two-year Conbercept therapy for diabetic macular edema.

Yong Cheng, Li Yuan, Ming-Wei Zhao, Tong Qian

Erratum issuedAbstract read
In one paragraph

Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Recent advances in the study of Conbercept for diabetic macular edema.International journal of retina and vitreous · 2025
    Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yong ChengDepartment of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.
Li YuanDepartment of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.
Ming-Wei ZhaoDepartment of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.
Tong QianDepartment of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the two-year outcomes of patients treated for diabetic macular edema (DME) with intravitreal Conbercept (IVC).

methodsThe clinical data of 30 DME patients (36 eyes) were retrospectively reviewed. The patients were treated with IVC for 3mo. Additional IVC was given at subsequent monthly visits, if needed (3+PRN). The patients were followed up for 24mo.

resultsThe best-corrected visual acuity (BCVA) at 24mo significantly increased (66.7±15.3 letters) in comparison with the baseline (54.4±15.4 letters,

conclusionIVC is safe and effective for the treatment of DME.

Indexed as

Conberceptdiabetic macular edemaintravitrealvisual acuity

Identifiers

PMID33747819
PMCPMC7930533

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.