ArticleJournal of clinical orthopaedics and trauma2021
The changing face of central chondrosarcoma of bone. One UK-based orthopaedic oncology unit's experience of 33 years referrals.
Article in Journal of clinical orthopaedics and trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- Wait, scan and then? Exploring the long-term natural course of 119 low-grade central cartilaginous lesions of the long bones with MRI follow-up.European radiology · 2026Article
- Imaging findings and complications after curettage of atypical cartilaginous tumors in long bones: a retrospective single-center cohort study.Skeletal radiology · 2026Article
- Article
- Deep learning for automated segmentation of central cartilage tumors on MRI.European radiology experimental · 2025Article
- Quality appraisal of radiomics-based studies on chondrosarcoma using METhodological RadiomICs Score (METRICS) and Radiomics Quality Score (RQS).Insights into imaging · 2025Article
- Chondrosarcoma evaluation using hematein-based x-ray staining and high-resolution 3D micro-CT: a feasibility study.European radiology experimental · 2024Article
- Prevalence and characteristics of benign cartilaginous tumours of the shoulder joint. An MRI-based study.Skeletal radiology · 2024Article
- Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations.Journal of bone oncology · 2023Article
- Fracture risk after intralesional curettage of atypical cartilaginous tumors.Journal of orthopaedic surgery and research · 2023Article
- Article
- [Primary malignant bone tumors].Orthopadie (Heidelberg, Germany) · 2023Article
- Primary Osseous Malignancies of the Spine.Diagnostics (Basel, Switzerland) · 2023Review
- Active surveillance of atypical cartilaginous tumours of bone: short term quality of life measurements.Journal of orthopaedic surgery and research · 2023Article
- Benign incidental do-not-touch bone lesions.The British journal of radiology · 2023Review
- The influence of site on the incidence and diagnosis of solitary central cartilage tumours of the femur. A 21Journal of clinical orthopaedics and trauma · 2022Article
- Midterm MRI Follow-Up of Untreated Enchondroma and Atypical Cartilaginous Tumors in the Long Bones.Cancers · 2021Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo ascertain the changing incidence over time of the three commonest primary sarcomas of bone. Data obtained with particular reference to central chondrosarcoma from the annual referral rate to a large UK-based specialist orthopaedic oncology unit. To discuss how the "barnyard pen" analogy of cancers previously applied to certain commoner cancers can also be applicable to central chondrosarcoma (CS) of bone. MATERIALS AND
methodsA retrospective review was conducted of a computerised database identifying all central cartilage tumours (CCT) of bone, including enchondroma and CS subtypes, between 1985 and 2018. These were compared with the referrals of the other two commonest primary sarcomas of bone, osteosarcoma and Ewing sarcoma.
resultsThere was a total of 1507 CS showing a 68% overall increase in annual referral rate/incidence over the study period. 68% cases were the borderline malignant lesions now known as atypical cartilaginous tumour (ACT). The annual referral rate/incidence of this entity increased by 194% over the 30 years. Whereas, the annual referral rate/incidence for osteosarcoma and Ewing sarcoma was static for the past 20 years.
conclusionThe annual incidence of central CS of bone showed a marked increase over the 33-year period as compared with both osteosarcoma and Ewing sarcoma. This is especially in the ACT category and is thought to be due to the increased provision of MRI scanning flagging up a rise in incidental findings. The spectrum of CCTs from benign to highly malignant elegantly fits the "barn yard" pen analogy and could prove useful as an explanatory tool for patients and clinicians unfamiliar with these diseases.
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