Evidence map›Paper›PMID 33747747›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Magneto-Based Synergetic Therapy for Implant-Associated Infections via Biofilm Disruption and Innate Immunity Regulation.

Jiaxing Wang, Lingtian Wang, Jiong Pan, Jinhui Zhao, Jin Tang, Dajun Jiang, Ping Hu, Weitao Jia, Jianlin Shi

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 105 citations in OpenAlex.

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  8. Mesoporous FeAdvanced healthcare materials · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiaxing WangDepartment of Orthopaedics Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China.
Lingtian WangDepartment of Orthopaedics Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China.
Jiong PanSchool of Chemical Science and Engineering Tongji University Shanghai 200092 China.
Jinhui ZhaoDepartment of Orthopaedics Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China.
Jin TangDepartment of Clinical Laboratory Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China.
Dajun JiangDepartment of Orthopaedics Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China.
Ping HuState Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China.
Weitao JiaDepartment of Orthopaedics Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China.
Jianlin ShiState Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China.ORCID https://orcid.org/0000-0001-8790-195X
Shanghai Jiao Tong University · CNChinese Academy of Sciences · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implant-associated infections (IAIs) are a common cause of orthopedic surgery failure due to microbial biofilm-induced antibiotic-resistance and innate immune inactivation. Thus, the destruction of microbial biofilm plays a key role in reducing IAIs. Herein, first, a magneto-based synergetic therapy (MST) is proposed and demonstrated against IAIs based on biofilm destruction. Under an alternating magnetic field (AMF), CoFe

Indexed as

immunotherapyimplant‐associated infectionsmagnetic nanoparticlesmagneto‐based synergetic therapynitric oxide

Identifiers

PMID33747747
PMCPMC7967068
OpenAlexW3129138150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.