Evidence map›Paper›PMID 33747725›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Wearable and Implantable Intraocular Pressure Biosensors: Recent Progress and Future Prospects.

Cheng Yang, Xinshuo Huang, Xiangling Li, Chengduan Yang, Tao Zhang, Qianni Wu, Dong Liu, Haotian Lin, Weirong Chen, Ning Hu and 1 more

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Ion-Pair-Tuned Ionogels for Broad-Range Linear Pressure Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Unperceivable Designs of Wearable Electronics.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Feasibility of smart intraocular lens.International journal of ophthalmology · 2024
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cheng YangState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.
Xinshuo HuangState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.
Xiangling LiState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.
Chengduan YangState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.
Tao ZhangState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.
Qianni WuState Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou 510060 China.
Dong LiuState Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou 510060 China.
Haotian LinState Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou 510060 China.
Weirong ChenState Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou 510060 China.
Ning HuState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.
Xi XieState Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology The First Affiliated Hospital of Sun Yat-Sen University Sun Yat-Sen University Guangzhou 510006 China.ORCID https://orcid.org/0000-0001-7406-8444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosensors worn on or implanted in eyes have been garnering substantial attention since being proven to be an effective means to acquire critical biomarkers for monitoring the states of ophthalmic disease, diabetes. Among these disorders, glaucoma, the second leading cause of blindness globally, usually results in irreversible blindness. Continuous intraocular pressure (IOP) monitoring is considered as an effective measure, which provides a comprehensive view of IOP changes that is beyond reach for the "snapshots" measurements by clinical tonometry. However, to satisfy the applications in ophthalmology, the development of IOP sensors are required to be prepared with biocompatible, miniature, transparent, wireless and battery-free features, which are still challenging with many current fabrication processes. In this work, the recent advances in this field are reviewed by categorizing these devices into wearable and implantable IOP sensors. The materials and structures exploited for engineering these IOP devices are presented. Additionally, their working principle, performance, and the potential risk that materials and device architectures may pose to ocular tissue are discussed. This review should be valuable for preferable structure design, device fabrication, performance optimization, and reducing potential risk of these devices. It is significant for the development of future practical IOP sensors.

Indexed as

biosensorscontact lens sensorsglaucomaintraocular implantable sensorsIOP sensor

Identifiers

PMID33747725
PMCPMC7967055

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.