Evidence map›Paper›PMID 33747676›Full record

ArticleIEEE access : practical innovations, open solutions2020

Assessment of speech and fine motor coordination in children with autism spectrum disorder.

Tanya Talkar, James R Williamson, Daniel Hannon, Hrishikesh M Rao, Sophia Yuditskaya, Kajal Claypool, Douglas Sturim, Lisa Nowinski, Hannah Saro, Carol Stamm and 3 more

Open access · goldAbstract read
In one paragraph

Article in IEEE access : practical innovations, open solutions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. An Acoustic Analysis of Speech Motor Performance in Autistic Children.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  6. Vocal and Facial Behavior During Affect Production in Autism Spectrum Disorder.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  7. Article
  8. An Emotion-Driven Vocal Biomarker-Based PTSD Screening Tool.IEEE open journal of engineering in medicine and biology · 2024
    Article
  9. Article
  10. Oromotor skills in autism spectrum disorder: A scoping review.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  11. Interpol questioned documents review 2019-2022.Forensic science international. Synergy · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. A Framework for Biomarkers of COVID-19 Based on Coordination of Speech-Production Subsystems.IEEE open journal of engineering in medicine and biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Tanya TalkarSpeech and Hearing Bioscience & Technology, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA.
James R WilliamsonHuman Health and Performance Systems, Massachusetts Institute of Technology Lincoln Laboratory, Lexington, MA 02142, USA.
Daniel HannonHuman Health and Performance Systems, Massachusetts Institute of Technology Lincoln Laboratory, Lexington, MA 02142, USA.
Hrishikesh M RaoHuman Health and Performance Systems, Massachusetts Institute of Technology Lincoln Laboratory, Lexington, MA 02142, USA.
Sophia YuditskayaHuman Health and Performance Systems, Massachusetts Institute of Technology Lincoln Laboratory, Lexington, MA 02142, USA.
Kajal ClaypoolHuman Health and Performance Systems, Massachusetts Institute of Technology Lincoln Laboratory, Lexington, MA 02142, USA.
Douglas SturimArtificial Intelligence Technology and Systems, Massachusetts Institute of Technology Lincoln Laboratory, Lexington, MA 02142, USA.
Lisa NowinskiMassachusetts General Hospital Lurie Center for Autism, Lexington, MA, 02421, USA.
Hannah SaroMassachusetts General Hospital Lurie Center for Autism, Lexington, MA, 02421, USA.
Carol StammMassachusetts General Hospital Lurie Center for Autism, Lexington, MA, 02421, USA.
Maria ModyMassachusetts General Hospital Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115.
Christopher J McDougleMassachusetts General Hospital Lurie Center for Autism, Lexington, MA, 02421, USA.
Thomas F QuatieriSpeech and Hearing Bioscience & Technology, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA.
MIT Lincoln Laboratory · USMassachusetts General Hospital · USHarvard University · US

Funding

TRAINING FOR SPEECH AND HEARING SCIENCEST32DC000038 · NIDCD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Gwenaelle S Geleoc · 1992 to 2026
$21.8M
NIDCD NIH HHS T32 DC000038
6 · The paper itself

Abstract

Autism Spectrum Disorder (ASD) is a developmental disorder characterized by difficulty in communication, which includes a high incidence of speech production errors. We hypothesize that these errors are partly due to underlying deficits in motor coordination and control, which are also manifested in degraded fine motor control of facial expressions and purposeful hand movements. In this pilot study, we computed correlations of acoustic, video, and handwriting time-series derived from five children with ASD and five children with neurotypical development during speech and handwriting tasks. These correlations and eigenvalues derived from the correlations act as a proxy for motor coordination across articulatory, laryngeal, and respiratory speech production systems and for fine motor skills. We utilized features derived from these correlations to discriminate between children with and without ASD. Eigenvalues derived from these correlations highlighted differences in complexity of coordination across speech subsystems and during handwriting, and helped discriminate between the two subject groups. These results suggest differences in coupling within speech production and fine motor skill systems in children with ASD. Our long-term goal is to create a platform assessing motor coordination in children with ASD in order to track progress from speech and motor interventions administered by clinicians.

Indexed as

acoustic speech analysisautism spectrum disorderbiomedical applicationfine motor skillsmotor coordination

Identifiers

PMID33747676
PMCPMC7971182
OpenAlexW3041256490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.