Evidence map›Paper›PMID 33747668›Full record

ArticleIEEE access : practical innovations, open solutions2020

Simultaneous Multi-Structure Segmentation of the Heart and Peripheral Tissues in Contrast Enhanced Cardiac Computed Tomography Angiography.

Vy Bui, Sujata M Shanbhag, Oscar Levine, Matthew Jacobs, W Patricia Bandettini, Lin-Ching Chang, Marcus Y Chen, Li-Yueh Hsu

Open access · goldAbstract read
In one paragraph

Article in IEEE access : practical innovations, open solutions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vy BuiNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Sujata M ShanbhagNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Oscar LevineNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Matthew JacobsNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
W Patricia BandettiniNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Lin-Ching ChangDepartment of Electrical Engineering and Computer Science, Catholic University of America, Washington DC, USA.
Marcus Y ChenNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Li-Yueh HsuNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · USUniversity of America · US

Funding

Cardiovascular CT Clinical ResearchZIAHL006220 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHEN, MARCUS · 2017 to 2025
$22.5M
Intramural NIH HHS Z99 HL999999Intramural NIH HHS ZIA HL006220
6 · The paper itself

Abstract

Contrast enhanced cardiac computed tomography angiography (CTA) is a prominent imaging modality for diagnosing cardiovascular diseases non-invasively. It assists the evaluation of the coronary artery patency and provides a comprehensive assessment of structural features of the heart and great vessels. However, physicians are often required to evaluate different cardiac structures and measure their size manually. Such task is very time-consuming and tedious due to the large number of image slices in 3D data. We present a fully automatic method based on a combined multi-atlas and corrective segmentation approach to label the heart and its associated cardiovascular structures. This method also automatically separates other surrounding intrathoracic structures from CTA images. Quantitative assessment of the proposed method is performed on 36 studies with a reference standard obtained from expert manual segmentation of various cardiac structures. Qualitative evaluation is also performed by expert readers to score 120 studies of the automatic segmentation. The quantitative results showed an overall Dice of 0.93, Hausdorff distance of 7.94 mm, and mean surface distance of 1.03 mm between automatically and manually segmented cardiac structures. The visual assessment also attained an excellent score for the automatic segmentation. The average processing time was 2.79 minutes. Our results indicate the proposed automatic framework significantly improves accuracy and computational speed in conventional multi-atlas based approach, and it provides comprehensive and reliable multi-structural segmentation of CTA images that is valuable for clinical application.

Indexed as

Computed tomographyheart segmentationmulti-atlas segmentationrandom walk

Identifiers

PMID33747668
PMCPMC7971052
OpenAlexW3000108223

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.