Evidence map›Paper›PMID 33747600›Full record

ArticleBiomedical engineering letters2021

Deep learning approach for the segmentation of aneurysmal ascending aorta.

Albert Comelli, Navdeep Dahiya, Alessandro Stefano, Viviana Benfante, Giovanni Gentile, Valentina Agnese, Giuseppe M Raffa, Michele Pilato, Anthony Yezzi, Giovanni Petrucci and 1 more

Open access · greenAbstract read
In one paragraph

Article in Biomedical engineering letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Albert ComelliRi.MED Foundation, Palermo, Italy.
Navdeep DahiyaDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA.
Alessandro StefanoInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefalù, Italy.
Viviana BenfanteInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefalù, Italy.
Giovanni GentileDepartment of Diagnostic and Therapeutic Services, Radiology Unit, IRCCS-ISMETT, Palermo, Italy.
Valentina AgneseDepartment for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT, Palermo, Italy.
Giuseppe M RaffaDepartment for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT, Palermo, Italy.
Michele PilatoDepartment for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT, Palermo, Italy.
Anthony YezziDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA.
Giovanni PetrucciDepartment of Engineering, University of Palermo, Palermo, Italy.
Salvatore PastaDepartment of Engineering, University of Palermo, Palermo, Italy.ORCID 0000-0002-4841-2560
Institute of Molecular Bioimaging and Physiology · ITIstituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione · ITGeorgia Institute of Technology · USUniversity of Palermo · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

Quantification of myocardial blood flow using Dynamic PET/CTA fused imagery to determine physiological significance of specific coronary lesionsR01HL143350 · NHLBI · EMORY UNIVERSITY · PI PICCINELLI, MARINA · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL143350
6 · The paper itself

Abstract

Diagnosis of ascending thoracic aortic aneurysm (ATAA) is based on the measurement of the maximum aortic diameter, but size is not a good predictor of the risk of adverse events. There is growing interest in the development of novel image-derived risk strategies to improve patient risk management towards a highly individualized level. In this study, the feasibility and efficacy of deep learning for the automatic segmentation of ATAAs was investigated using UNet, ENet, and ERFNet techniques. Specifically, CT angiography done on 72 patients with ATAAs and different valve morphology (i.e., tricuspid aortic valve, TAV, and bicuspid aortic valve, BAV) were semi-automatically segmented with Mimics software (Materialize NV, Leuven, Belgium), and then used for training of the tested deep learning models. The segmentation performance in terms of accuracy and time inference were compared using several parameters. All deep learning models reported a dice score higher than 88%, suggesting a good agreement between predicted and manual ATAA segmentation. We found that the ENet and UNet are more accurate than ERFNet, with the ENet much faster than UNet. This study demonstrated that deep learning models can rapidly segment and quantify the 3D geometry of ATAAs with high accuracy, thereby facilitating the expansion into clinical workflow of personalized approach to the management of patients with ATAAs.

Indexed as

AneurysmAortaAortic valveDeep learningSegmentation

Identifiers

PMID33747600
PMCPMC7930147
OpenAlexW3108981504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.