Evidence map›Paper›PMID 33747398›Full record

ArticleMediterranean journal of hematology and infectious diseases2021

Real-World Data on Characteristics and Management of Community Patients Receiving Anticoagulation Therapy Who Presented with Acute Bleeding to the Emergency Department at a Regional Australian Hospital: A Prospective Observational Study.

Fayez Hanna, Annemarie Hyppa, Ajay Prakash, Usira Vithanarachchi, Hizb U Dawar, Zar Sanga, George Olabode, Hamish Crisp, Alhossain A Khalafallah

Open access · goldAbstract read
In one paragraph

Article in Mediterranean journal of hematology and infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Fayez HannaFaculty of Health Sciences, Launceston, University of Tasmania, Tasmania, 7249, Australia.
Annemarie HyppaDepartment of Haematology, Specialist Care Australia, Launceston, Tasmania, 7250 Australia.
Ajay PrakashFaculty of Health Sciences, Launceston, University of Tasmania, Tasmania, 7249, Australia.
Usira VithanarachchiFaculty of Health Sciences, Launceston, University of Tasmania, Tasmania, 7249, Australia.
Hizb U DawarAugusta Medical Centre, Lenah Valley 7008, Tasmania, Australia.
Zar SangaAugusta Medical Centre, Lenah Valley 7008, Tasmania, Australia.
George OlabodeLaunceston General Hospital, Launceston, Tasmania, 7250 Australia.
Hamish CrispLaunceston General Hospital, Launceston, Tasmania, 7250 Australia.
Alhossain A KhalafallahFaculty of Health Sciences, Launceston, University of Tasmania, Tasmania, 7249, Australia.
University of Tasmania · AUAugusta University · USLaunceston General Hospital · AUSaarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study patients receiving anticoagulants with or without antiplatelet therapy presenting at a regional Australian hospital with bleeding. The main aims are to explore: (1) patients' characteristics and management provided; (2) association between the type of anticoagulant and antiplatelet agent used and the requirement of reversal; (3) and the length of hospital stay (LoS) in conjunction with bleeding episode and management.

methodsA prospective cross-sectional review of medical records of all patients who presented at a tertiary referral centre with bleeding while receiving anticoagulation therapy between January 2016 and June 2018. Data included: patients, demographics, investigations (kidney and liver function tests, coagulation profile, FBC), LoS, bleeding site, type of and reason for anticoagulation therapy, and management provided. Data analysis included descriptive statistics, χ

resultsAmong the 144 eligible patients, 75 (52.1%) were male, and the mean age was 76 years (

conclusionWarfarin use was common among patients who presented with acute bleeding, and the INR in many warfarinised patients exceeded the target for their condition. DOACs were associated with a reduced likelihood of receiving reversal and a shorter LoS than warfarin, LMWH, which might support a broader application of DOACs into community practice.

Indexed as

AnticoagulationAntiplateletsBleedingDOACLength of Hospital stayOutcomeReversal

Identifiers

PMID33747398
PMCPMC7938926
OpenAlexW3135765958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.