Evidence map›Paper›PMID 33747210›Full record

ArticleOncology letters2021

Potential application of genomic profiling for the diagnosis and treatment of patients with sarcoma.

Libin Xu, Xianbiao Xie, Xiaoliang Shi, Peng Zhang, Angen Liu, Jian Wang, Bo Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Future oncology (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Libin XuDepartment of Orthopedic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, P.R. China.
Xianbiao XieDepartment of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat Sen University, Guangzhou, Guangdong 510080, P.R. China.
Xiaoliang ShiOrigiMed Co. Ltd., Shanghai 201114, P.R. China.
Peng ZhangOrigiMed Co. Ltd., Shanghai 201114, P.R. China.
Angen LiuOrigiMed Co. Ltd., Shanghai 201114, P.R. China.
Jian WangDepartment of Pathology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Bo ZhangDepartment of Pathology, Peking University Third Hospital, Beijing 100191, P.R. China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNFudan University Shanghai Cancer Center · CNPeking University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcomas represent a heterogeneous group of mesenchymal malignancies arising at various locations in the soft tissue and bone. Though a rare disease, sarcoma affects ~200,000 patients worldwide every year. The prognosis of patients with sarcoma is poor, and targeted therapy options are limited; therefore, accurate diagnosis and classification are essential for effective treatment. Sarcoma samples were acquired from 199 patients, in which

Indexed as

biomarkerdiagnosisgenomic profilingnext-generation sequencingsarcomatumor mutational burden

Identifiers

PMID33747210
PMCPMC7967939
OpenAlexW3134550072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.