Evidence map›Paper›PMID 33747130›Full record

ArticleTherapeutic advances in neurological disorders2021

Blood pressure variability and outcomes after mechanical thrombectomy based on the recanalization and collateral status.

Xianjun Huang, Hongquan Guo, Lili Yuan, Qiankun Cai, Min Zhang, Yi Zhang, Wusheng Zhu, Zibao Li, Qian Yang, Zhiming Zhou and 2 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in neurological disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Under (back) pressure: Better collateral flow may facilitate clot removal in ischemic stroke: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
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  9. Prognostic value of beat-to-beat blood pressure variability parameters in patients after mechanical thrombectomy.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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  15. Good outcome associated with blood-brain barrier disruption and lower blood pressure after endovascular therapy.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
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  17. Association between CHADSJournal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Xianjun HuangDepartment of Neurology, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, Jiangsu Province, China.ORCID https://orcid.org/0000-0003-2646-982X
Hongquan GuoDepartment of Neurology, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, Jiangsu Province, China.
Lili YuanDepartment of Neurology, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui Province, China.
Qiankun CaiDepartment of Neurology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.
Min ZhangDepartment of Neurology, Jinling Clinical College of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Yi ZhangDepartment of Neurology, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, Jiangsu Province, China.
Wusheng ZhuDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Zibao LiDepartment of Neurology, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui Province, China.
Qian YangDepartment of Neurology, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui Province, China.
Zhiming ZhouDepartment of Neurology, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui Province, China.
Wen SunStroke Center & Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui Province, China.
Xinfeng LiuDepartment of Neurology, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, 305# East Zhongshan Road, Nanjing, Jiangsu Province 210002, China.ORCID https://orcid.org/0000-0002-8182-9632
Wannan Medical College · CNNanjing General Hospital of Nanjing Military Command · CNFujian Medical University · CNNanjing Medical University · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood pressure (BP), recanalization status, and collateral circulation are important factors for cerebral autoregulation after stroke. We aimed to investigate the association of various BP variability (BPV) parameters with clinical outcomes after mechanical thrombectomy (MT) according to recanalization and collateral status.

methodsWe included 502 consecutive patients who underwent MT due to anterior circulation large vessel occlusion stroke at three comprehensive stroke centers. BPV parameters were standard deviation (SD), maximum/minimum BP, coefficient of variation (CV) and successive variation (SV). The clinical outcomes included 90-day functional outcome assessed by modified Rankin Scale score and symptomatic intracranial hemorrhage (sICH).

resultsAmong the included patients, 219 (43.6%) achieved good functional outcomes and 59 (11.8%) developed sICH. After adjusting for confounders, higher systolic BP (SBP) variability [CV (odds ratio (OR), 1.089,

conclusionsHigher SBP SD and CV during the first 24 h after MT was a powerful predictor of worse clinical outcomes, regardless of the collateral status. However, the effects of BPV on outcomes were more substantial among patients with successful reperfusion.

Indexed as

blood pressuremechanical thrombectomyprognosisstrokevariability

Identifiers

PMID33747130
PMCPMC7940733
OpenAlexW3135639504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.