Evidence map›Paper›PMID 33747078›Full record

ArticleInternational journal of endocrinology2021

High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome.

Tao Hong, Jiao-Yang Li, Ya-Di Wang, Xiao-Yan Qi, Zhe-Zhen Liao, Poonam Bhadel, Li Ran, Jing Yang, Bin Yan, Jiang-Hua Liu and 1 more

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05471388 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Assessment of Serum Asprosin Level in Male Patients With Acne Vulgaris

TypeinterventionalSponsorSohag UniversityRan2022 to 2023Enrolled72ConditionsAcne VulgarisArmsserum asprosin
NCT05943158 nacompletednot on this map

Effect of Myoinositol on Serum Asprosin Levels in Pregnant Women

TypeinterventionalSponsorNear East University, TurkeyRan2021 to 2023Enrolled40ConditionsPregnancy RelatedArmsmyoinositol and folic acid, folic acid
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tao HongDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Jiao-Yang LiDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Ya-Di WangDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Xiao-Yan QiDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Zhe-Zhen LiaoDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Poonam BhadelDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Li RanDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Jing YangDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Bin YanDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.
Jiang-Hua LiuDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.ORCID https://orcid.org/0000-0003-3010-5113
Xin-Hua XiaoDepartment of Metabolism and Endocrinology, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, China.ORCID https://orcid.org/0000-0002-2706-4464
First Affiliated Hospital of University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAsprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). However, the relationship of asprosin with metabolic syndrome (MetS) remains unknown. This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in humans.

methodsA total of 131 consecutive patients with MetS, and 162 age-matched, healthy subjects were recruited for this study. Serum asprosin concentrations were determined using the enzyme-linked immunosorbent assay. Lipid profile, glucose, insulin, and inflammatory markers were also measured.

resultsSerum asprosin levels were higher in subjects with MetS (23.52 [16.70, 32.05] ng/mL) than in controls (16.70 [12.87, 22.38] ng/mL;

conclusionAsprosin is a potential metabolic-related adipokine and may be related to IR and MetS. This trial was registered with ChiCTR, ChiCTR1800018347.

Identifiers

PMID33747078
PMCPMC7943292
OpenAlexW3135028392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.