ReviewFrontiers in plant science2021
A Review of Nervonic Acid Production in Plants: Prospects for the Genetic Engineering of High Nervonic Acid Cultivars Plants.
Review in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Advancements in Crop PUFAs Biosynthesis and Genetic Engineering: A Systematic and Mixed Review System.International journal of molecular sciences · 2025Pooled it
- The chromosome-level genomes of twoHorticulture research · 2026Article
- Review
- Metabolic Pathways and Molecular Regulatory Mechanisms of Nervonic Acid Biosynthesis inInternational journal of molecular sciences · 2026Review
- EngineeringSynthetic and systems biotechnology · 2026Article
- Metabolomics analysis reveals kernel quality variation among main yellowhorn (Xanthoceras sorbifolium Bunge) cultivars.BMC plant biology · 2026Article
- A Synergistic Genetic Engineering Strategy Induced Nervonic Acid inInternational journal of molecular sciences · 2026Article
- Prediction of potential suitable habitats of Malania oleifera under future climate scenarios based on the MaxEnt model.Scientific reports · 2025Article
- Photobiota of the Tropical Red Sea: Fatty Acid Profile Analysis and Nutritional Quality Assessments.Molecules (Basel, Switzerland) · 2025Article
- Population variation in fatty acid composition and response to climatic factors in Malania oleifera Chun et S.K. Lee.BMC plant biology · 2025Article
- Nervonic acid in infant nutrition: a forward-looking approach to enhancing neurodevelopmental outcomes.Frontiers in nutrition · 2025Review
- Review
- Cultivated Winter-TypeMolecules (Basel, Switzerland) · 2024Article
- Integrated analysis of metabolome, transcriptome, and bioclimatic factors of Acer truncatum seeds reveals key candidate genes related to unsaturated fatty acid biosynthesis, and potentially optimal production area.BMC plant biology · 2024Article
- Valorization of Chlorella thermophila biomass cultivated in dairy wastewater for biopesticide production against bacterial rice blight: a circular biorefinery approach.BMC plant biology · 2023Article
- Nervonic acid reduces the cognitive and neurological disturbances induced by combined doses of D-galactose/AlClFood science & nutrition · 2023Article
- Current advances in alteration of fatty acid profile in Rhodotorula toruloides: a mini-review.World journal of microbiology & biotechnology · 2023Review
- Unveiling the MUFA-Cancer Connection: Insights from Endogenous and Exogenous Perspectives.International journal of molecular sciences · 2023Review
- The chromosome-level genome assembly and genes involved in biosynthesis of nervonic acid of Malania oleifera.Scientific data · 2023Article
- High-quality genome assembly and comparative genomic profiling of yellowhorn (Frontiers in plant science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nervonic acid (NA) is a very-long-chain monounsaturated fatty acid that plays crucial roles in brain development and has attracted widespread research interest. The markets encouraged the development of a refined, NA-enriched plant oil as feedstocks for the needed further studies of NA biological functions to the end commercial application. Plant seed oils offer a renewable and environmentally friendly source of NA, but their industrial production is presently hindered by various factors. This review focuses on the NA biosynthesis and assembly, NA resources from plants, and the genetic engineering of NA biosynthesis in oil crops, discusses the factors that affect NA production in genetically engineered oil crops, and provides prospects for the application of NA and prospective trends in the engineering of NA. This review emphasizes the progress made toward various NA-related topics and explores the limitations and trends, thereby providing integrated and comprehensive insight into the nature of NA production mechanisms during genetic engineering. Furthermore, this report supports further work involving the manipulation of NA production through transgenic technologies and molecular breeding for the enhancement of crop nutritional quality or creation of plant biochemical factories to produce NA for use in nutraceutical, pharmaceutical, and chemical industries.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.