Evidence map›Paper›PMID 33746920›Full record

ArticleFrontiers in microbiology2021

Elevated β-Carotene Production Using Codon-Adapted CarRA&B and Metabolic Balance in Engineered

Liang Liu, Yu Ling Qu, Gui Ru Dong, Jing Wang, Ching Yuan Hu, Yong Hong Meng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Metabolic Engineering ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Engineering ofMetabolic engineering communications · 2022
    Review
  9. Article
  10. Carotenoids and Their Biosynthesis in Fungi.Molecules (Basel, Switzerland) · 2022
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Liang LiuEngineering Research Center of High Value Utilization of Western China Fruit Resources, Ministry of Education, National Research and Development Center of Apple Processing Technology, Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Yu Ling QuEngineering Research Center of High Value Utilization of Western China Fruit Resources, Ministry of Education, National Research and Development Center of Apple Processing Technology, Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Gui Ru DongEngineering Research Center of High Value Utilization of Western China Fruit Resources, Ministry of Education, National Research and Development Center of Apple Processing Technology, Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Jing WangEngineering Research Center of High Value Utilization of Western China Fruit Resources, Ministry of Education, National Research and Development Center of Apple Processing Technology, Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Ching Yuan HuEngineering Research Center of High Value Utilization of Western China Fruit Resources, Ministry of Education, National Research and Development Center of Apple Processing Technology, Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Yong Hong MengEngineering Research Center of High Value Utilization of Western China Fruit Resources, Ministry of Education, National Research and Development Center of Apple Processing Technology, Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Shaanxi Normal University · CNUniversity of Hawaiʻi at Mānoa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-carotene is a precursor of vitamin A and has multiple physiological functions. Producing β-carotene by microbial fermentation has attracted much attention to consumers' preference for natural products. This study focused on improving β-carotene production by constructing codon-adapted genes and minimizing intermediate accumulation. The codon-adapted

Indexed as

CarBCarRAmetabolic balanceYarrowia lipolyticaβ-carotene

Identifiers

PMID33746920
PMCPMC7970187
OpenAlexW3135818560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.