Evidence map›Paper›PMID 33746772›Full record

ArticleFrontiers in physiology2021

High Fat Diet Dysbiotic Mechanism of Decreased Gingival Blood Flow.

Dragana Stanisic, Nevena Jeremic, Suravi Majumder, Sathnur Pushpakumar, Akash George, Mahavir Singh, Suresh C Tyagi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. A systematic review and meta-analysis of the effects of probiotics on bone outcomes in rodent models.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Periodontal bacteria influence systemic diseases through the gut microbiota.Frontiers in cellular and infection microbiology · 2024
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Dragana StanisicDepartment of Dentistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Nevena JeremicDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, United States.
Suravi MajumderDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, United States.
Sathnur PushpakumarDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, United States.
Akash GeorgeDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, United States.
Mahavir SinghDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, United States.
Suresh C TyagiDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, United States.
University of Louisville · US

Funding

miRNA Mechanism of Acute Kidney Injury in AgingR01DK116591 · NIDDK · UNIVERSITY OF LOUISVILLE · PI SEN, UTPAL, TYAGI, SURESH C. · 2018 to 2022
$2.2M
Remote Hind Limb Ischemia Mechanism of CardioprotectionR01HL139047 · NHLBI · UNIVERSITY OF LOUISVILLE · PI TYAGI, SURESH C. · 2018 to 2021
$1.8M
Reversing Skeletal Muscle Myopathy by Hydrogen SulfideR01AR071789 · NIAMS · UNIVERSITY OF LOUISVILLE · PI TYAGI, SURESH C. · 2018 to 2023
$1.7M
NHLBI NIH HHS R01 HL139047NIAMS NIH HHS R01 AR071789NIDDK NIH HHS R01 DK116591
6 · The paper itself

Abstract

The gut microbiome has a very important role in human health and its influence on the development of numerous diseases is well known. In this study, we investigated the effect of high fat diet (HFD) on the onset of dysbiosis, gingival blood flow decreases, and the periodontal matrix remodeling. We established a dysbiosis model (HFD group) and probiotic model by

Indexed as

blood flowgut microbiotaLactobacillus rhamnosusLaser Doppler flowmetrylipopolysaccharidematrix metalloproteinasesperiodontal disease

Identifiers

PMID33746772
PMCPMC7965981
OpenAlexW3135656228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.