Evidence map›Paper›PMID 33746770›Full record

ReviewFrontiers in physiology2021

The Normal and Brain Tumor Vasculature: Morphological and Functional Characteristics and Therapeutic Targeting.

Joris Guyon, Candice Chapouly, Laetitia Andrique, Andreas Bikfalvi, Thomas Daubon

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Obstacles and Trials in Treating Primary Brain Tumors.International journal of molecular sciences · 2026
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  12. Practical immunomodulatory landscape of glioblastoma multiforme (GBM) therapy.Journal of the Egyptian National Cancer Institute · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joris GuyonINSERM, LAMC, U1029, University Bordeaux, Pessac, France.
Candice ChapoulyINSERM, Biology of Cardiovascular Diseases, U1034, University Bordeaux, Pessac, France.
Laetitia AndriqueINSERM, LAMC, U1029, University Bordeaux, Pessac, France.
Andreas BikfalviINSERM, LAMC, U1029, University Bordeaux, Pessac, France.
Thomas DaubonUniversity Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma is among the most common tumor of the central nervous system in adults. Overall survival has not significantly improved over the last decade, even with optimizing standard therapeutic care including extent of resection and radio- and chemotherapy. In this article, we review features of the brain vasculature found in healthy cerebral tissue and in glioblastoma. Brain vessels are of various sizes and composed of several vascular cell types. Non-vascular cells such as astrocytes or microglia also interact with the vasculature and play important roles. We also discuss

Indexed as

antiangiogenic therapyastrocyteblood vesselsbrainglioblastomavascular tissue engineering

Identifiers

PMID33746770
PMCPMC7973205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.