ArticleFrontiers in cellular neuroscience2021
The Theta Rhythm of the Hippocampus: From Neuronal and Circuit Mechanisms to Behavior.
Article in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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80 citing papers in PubMed.
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- Universal rhythmic architecture uncovers two modes of neural dynamics.Nature communications · 2026Article
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- Comparison of Resting-State EEG and Synchronization Between Young Adults with Down Syndrome and Controls in Bipolar Montage.Brain sciences · 2026Article
- Bilingualism modulates functional connectivity induced by a domain-general artificial grammar learning task.Scientific reports · 2026Article
- Multimodal evidence for hippocampal engagement and modulation by functional connectivity-guided parietal TMS.Nature communications · 2026Article
- Temporally Defined Brain Network Activation Associated With Slowed Information Processing Speed in Multiple Sclerosis.Human brain mapping · 2026Article
- Acute ethanol enhances septohippocampal coordination but disrupts intrinsic hippocampal theta dynamics during foraging.Alcohol (Fayetteville, N.Y.) · 2026Article
- Integrating memory-guided saccades and EEG for MCI screening: a multimodal LASSO modeling approach.Frontiers in aging neuroscience · 2026Article
- Multimodal hypersensitivity and somatic symptoms predict adolescent postmenarchal widespread pain.Pain · 2025Article
- The medial septum-hippocampus-lateral septum circuitry in spatial memory: linking healthy function to early Alzheimer's disease and translational opportunities.Translational neurodegeneration · 2025Review
- REM sleep prefrontal ripple chains mediate distinct cortical-hippocampal reactivation patterns compared to NREM ripples.bioRxiv : the preprint server for biology · 2025Article
- Comparison of overnight trends in relative power for specific frequency bands, sleep stages, and brain regions between patients with depressive disorder and matched control subjects.Psychiatry research. Neuroimaging · 2025Article
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- Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity.PLoS computational biology · 2025Article
- The lateralized LC-NAergic system distinguishes vicarious versus direct fear in mice.Nature communications · 2025Article
- Reduction in EEG theta power as a potential marker for spatial disorientation during flight.Scientific reports · 2025Article
20 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
This review focuses on the neuronal and circuit mechanisms involved in the generation of the theta (θ) rhythm and of its participation in behavior. Data have accumulated indicating that θ arises from interactions between medial septum-diagonal band of Broca (MS-DbB) and intra-hippocampal circuits. The intrinsic properties of MS-DbB and hippocampal neurons have also been shown to play a key role in θ generation. A growing number of studies suggest that θ may represent a timing mechanism to temporally organize movement sequences, memory encoding, or planned trajectories for spatial navigation. To accomplish those functions, θ and gamma (γ) oscillations interact during the awake state and REM sleep, which are considered to be critical for learning and memory processes. Further, we discuss that the loss of this interaction is at the base of various neurophatological conditions.
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