Evidence map›Paper›PMID 33746642›Full record

ArticleCurrent sexual health reports2020

The Seminal Microbiome and Male Factor Infertility.

Vadim Osadchiy, Jesse N Mills, Emeran A Mayer, Sriram V Eleswarapu

Abstract read
In one paragraph

Article in Current sexual health reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Microbial Landscape of Bull (Animals : an open access journal from MDPI · 2026
    Article
  2. Review
  3. Review
  4. Understanding the Associations of Urogenital Microbiomes With Fertility and In Vitro Fertilization.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Human genital tracts microbiota: dysbiosis crucial for infertility.Journal of endocrinological investigation · 2022
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vadim OsadchiyDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles.
Jesse N MillsDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles.
Emeran A MayerVatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles.
Sriram V EleswarapuDivision of Andrology, Department of Urology, David Geffen School of Medicine, University of California, Los Angeles.

Funding

Neurobiological endophenotypes & gene-environment interactions in IC/PBS & in aU01DK082370 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KUTCH, JASON J., MAYER, EMERAN A · 2008 to 2021
$9.2M
PERCEPTION AND MODULATION OF VISCERAL SENSATIONSR01DK048351 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 1996 to 2019
$8.2M
NIDDK NIH HHS R01 DK048351NIDDK NIH HHS U01 DK082370
6 · The paper itself

Abstract

purpose of reviewFocusing on studies published within the last decade, we review the literature on the seminal microbiome and male factor infertility. We highlight potential mechanisms by which microbes may impact fertility and underscore key limitations and clinical implications of these studies. RECENT

findingsThe seminal microbiome encompasses a metabolically and phylogenetically diverse group of microorganisms. SUMMARY: Research investigating the intersection between the seminal microbiome and male fertility is still in its infancy. Recent investigations have been exclusively cross-sectional, correlational studies, limiting the clinical applicability of published research. Prospective studies with more sophisticated methodologies are necessary.

Indexed as

AnaerococcusMale InfertilityNext Generation SequencingSemen Microbiome

Identifiers

PMID33746642
PMCPMC7968069

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.