Evidence map›Paper›PMID 33746630›Full record

ArticleMolecular imaging2021

Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System.

Maritina Rouchota, Alessio Adamiano, Michele Iafisco, Eirini Fragogeorgi, Irineos Pilatis, Gilles Doumont, Sébastien Boutry, Daniele Catalucci, Argyro Zacharioudaki, George C Kagadis

Open access · goldAbstract read
In one paragraph

Article in Molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Maritina Rouchota3dmi Research Group, Department of Medical Physics, School of Medicine, University of Patras, Greece.ORCID 0000-0003-1988-0426
Alessio AdamianoInstitute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Italy.
Michele IafiscoInstitute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Italy.
Eirini FragogeorgiInstitute of Nuclear & Radiological Sciences, Technology, Energy & Safety, NCSR "Demokritos", Greece.
Irineos PilatisDepartment of Biomedical Engineering, University of West Attica, Greece.
Gilles DoumontCenter for Microscopy and Molecular Imaging (CMMI), Université Libre de Bruxelles (ULB), Rue Adrienne Bolland 8, B-6041 Charleroi (Gosselies), Belgium.
Sébastien BoutryCenter for Microscopy and Molecular Imaging (CMMI), Université Libre de Bruxelles (ULB), Rue Adrienne Bolland 8, B-6041 Charleroi (Gosselies), Belgium.
Daniele CatalucciInstitute of Genetic and Biomedical Research (IRGB), National Research Council (CNR), UOS Milan, Italy.
Argyro ZacharioudakiDVM MLAS Dipl.ECLAM, Greece.
George C Kagadis3dmi Research Group, Department of Medical Physics, School of Medicine, University of Patras, Greece.
Institute of Science and Technology for Ceramics · ITUniversité Libre de Bruxelles · BEUniversity of Patras · GRHumanitas University · ITMawlamyine University · MMNational Centre of Scientific Research "Demokritos" · GRUniversity of West Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular imaging holds great promise in the noninvasive monitoring of several diseases with nanoparticles (NPs) being considered an efficient imaging tool for cancer, central nervous system, and heart- or bone-related diseases and for disorders of the mononuclear phagocytic system (MPS). In the present study, we used an iron-based nanoformulation, already established as an MRI/SPECT probe, as well as to load different biomolecules, to investigate its potential for nuclear planar and tomographic imaging of several target tissues following its distribution via different administration routes. Iron-doped hydroxyapatite NPs (FeHA) were radiolabeled with the single photon

Indexed as

NanoparticlesAnimalsMagnetic Iron Oxide NanoparticlesMiceTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedWorkflow

Identifiers

PMID33746630
PMCPMC7953590
OpenAlexW3125095813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.