Evidence map›Paper›PMID 33746224›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2021

Endoscopic surgical treatment of epistaxis in hereditary haemorrhagic telangiectasia: our experience.

Fabio Pagella, Alessandro Pusateri, Eugenia Maiorano, Giuseppe Spinozzi, Sara Ugolini, Roberta Lizzio, Rosolino Mirabella, Carmine Tinelli, Carla Olivieri, Elina Matti

Open access · goldAbstract read
In one paragraph

Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Silicone septal splint for recurrent epistaxis in HHT patients: experience of a national referral centre.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Fabio PagellaDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Alessandro PusateriDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Eugenia MaioranoDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Giuseppe SpinozziDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Sara UgoliniDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Roberta LizzioDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Rosolino MirabellaDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Carmine TinelliClinical Epidemiology and Biometric Unit, Fondazione I.R.C.C.S. Policlinico San Matteo, Pavia, Italy.
Carla OlivieriUniversity of Pavia, Italy.
Elina MattiDepartment of Otorhinolaryngology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Policlinico San Matteo Fondazione · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHereditary haemorrhagic telangiectasia (HHT) is a rare autosomal dominant disease characterised by epistaxis. Surgical procedures for epistaxis vary from diathermocoagulation to nasal closure. The aim of this paper is to report our experience in endoscopic surgical management of epistaxis in HHT patients.

methodsThis is a descriptive, longitudinal study carried out at the Otorhinolaryngology Department of IRCCS Policlinico San Matteo in Pavia, a reference centre for the treatment and diagnosis of HHT. We retrospectively evaluated HHT patients who underwent surgery for epistaxis from 1996 to 2015, including only those treated with endoscopic surgery.

resultsAmong the 591 patients hospitalised and screened for HHT, 323 (54.7%) underwent endoscopic surgery for epistaxis, for a total of 679 procedures. General anaesthesia was used in 77.2% of procedures; argon plasma coagulation was the instrument of choice in the majority of patients, followed by lasers and quantum molecular resonance technology.

conclusionsWe report one of the largest cohorts undergoing endoscopic treatment of epistaxis in HHT patients. This mini-invasive surgical treatment allowed us to control epistaxis without major complications and nasal packaging and can be repeated over time. For these reasons, we recommend it as first choice in case of epistaxis in HHT patients.

Indexed as

EndoscopyEpistaxisTelangiectasia, Hereditary HemorrhagicHumansLongitudinal StudiesRetrospective Studiesargon plasma coagulationendoscopyepistaxishereditary haemorrhagic telangiectasianosebleedsRendu Osler Weber disease

Identifiers

PMID33746224
PMCPMC7982753
OpenAlexW3139125166

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.