Observational studyMedical science monitor : international medical journal of experimental and clinical research2021
A Single-Center Observational Clinical Study on Factors Associated with Regional Cerebral Oxygen Saturation in Full-Term Newborn Infants During Birth Transition.
Observational study in Medical science monitor : international medical journal of experimental and clinical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed, 2 citations in OpenAlex.
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5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Hypoxic hypoperfusion injury in the brain is a cause of potential injury and even death in the growth period of newborns. Therefore, monitoring regional cerebral oxygen saturation (CrSO₂) during this period is particularly important. This observational clinical study from a single center aimed to investigate the factors associated with CrSO₂ in full-term newborn infants during birth transition. MATERIAL AND METHODS We enrolled 84 full-term newborn infants delivered by cesarean section. We started the stopwatch with the obstetrician clamping the newborns' umbilical cords and recorded the values of newborns' CrSO₂, pulse oxygen saturation (SpO₂), pulse rate (PR), end-tidal carbon dioxide (EtCO₂), and respiratory rate (RR) at 2 min, 5 min, and 10 min. We weighed the newborns before they left the operating room and used statistical methods to compare the correlation between each observation factor. RESULTS Pearson correlation coefficients between CrSO₂ and SpO₂ measured at 2 min, 5 min, and 10 min were 0.491, 0.599, and 0.587, respectively (P<0.01). Pearson correlation coefficients between CrSO₂ and EtCO₂ measured at 2 min, 5 min, and 10 min were -0.304, -0.443, and -0.243, respectively (P<0.05). Regardless of a newborn's weight, PR, or RR, the correlation between any of those factors and the value of CrSO₂ measured at the corresponding time point had no significance (P>0.05). CONCLUSIONS This study showed a correlation between CrSO₂ and SpO₂ and CrSO₂ and EtCO₂ during birth transition of full-term infants delivered by elective cesarean section, but CrSO₂ had no significant correlation with neonatal weight, PR, or RR.
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