Evidence map›Paper›PMID 33745988›Full record

ReviewChest2021

Sex and Gender Omic Biomarkers in Men and Women With COPD: Considerations for Precision Medicine.

Dawn L DeMeo

Open access · greenAbstract readReview
In one paragraph

Review in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Asthma Exacerbations: The Genes Behind the Scenes.Journal of investigational allergology & clinical immunology · 2023
    Review
  11. Review
  12. Article
  13. Review
  14. Impact of Sex on Circulating Leukocytes Composition in COPD Patients.International journal of chronic obstructive pulmonary disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dawn L DeMeoChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address: DDemeo@partners.org.
Harvard University · US

Funding

Systems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2016 to 2020
$12.6M
Epitranscriptomics of the aging lungR21HL156122 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2021 to 2022
$492k
NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R21 HL156122
6 · The paper itself

Abstract

Sex and gender differences in lung health and disease are imperative to consider and study if precision pulmonary medicine is to be achieved. The development of reliable COPD biomarkers has been elusive, and the translation of biomarkers to clinical care has been limited. Useful and effective biomarkers must be developed with attention to clinical heterogeneity of COPD; inherent heterogeneity exists related to grouping women and men together in the studies of COPD. Considering sex and gender differences and influences related to -omics may represent progress in susceptibility, diagnostic, prognostic, and therapeutic biomarker development and clinical innovation to improve the lung health of men and women.

Indexed as

BiomarkersFemaleGlobal HealthHumansLungMaleMorbidityPrecision MedicinePulmonary Disease, Chronic ObstructiveSex FactorsBiomarkersbiomarkersCOPDgender-omicsprecision medicinesex

Identifiers

PMID33745988
PMCPMC8295903
OpenAlexW3136800591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.