Evidence map›Paper›PMID 33745816›Full record

ArticleAmerican journal of preventive medicine2021

Characteristics Associated With Opioid and Antibiotic Prescribing by Dentists.

Colin C Hubbard, Charlesnika T Evans, Gregory S Calip, Susan A Rowan, Walid F Gellad, Allen Campbell, Alan E Gross, Ronald C Hershow, Jessina C McGregor, Lisa K Sharp and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
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  5. Dental Pain Medication Prescriptions in Minas Gerais, Brazil (2011-2021): A Time-Series Analysis.International journal of environmental research and public health · 2023
    Article
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  12. A qualitative approach to examining antimicrobial prescribing in the outpatient dental setting.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Colin C HubbardDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois.
Charlesnika T EvansDepartment of Preventive Medicine, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Center of Innovation for Complex Chronic Healthcare, Edward Hines, Jr. VA Hospital, Hines, Illinois.
Gregory S CalipDepartment of Pharmacy Systems, Outcomes and Policy, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois.
Susan A RowanDepartment of Restorative Dentistry, College of Dentistry, University of Illinois Chicago, Chicago, Illinois.
Walid F GelladCenter for Health Equity Research and Promotion, VA Pittsburgh Health Care System, Pittsburgh, Pennsylvania; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Allen CampbellIQVIA Institute, Durham, North Carolina.
Alan E GrossDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois.
Ronald C HershowDepartment of Epidemiology, School of Public Health, University of Illinois Chicago, Chicago, Illinois.
Jessina C McGregorDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University, Corvallis, Oregon.
Lisa K SharpDepartment of Pharmacy Systems, Outcomes and Policy, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois.
Katie J SudaCenter for Health Equity Research and Promotion, VA Pittsburgh Health Care System, Pittsburgh, Pennsylvania; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: ksuda@pitt.edu.
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · USEdward Hines, Jr. VA Hospital · USIQVIA (United States) · USOregon State University · USUniversity of Pittsburgh · USVA Pittsburgh Healthcare System · US

Funding

Dental prescribing of antibiotics and opioids: high use in the absence of evidenceR01HS025177 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SUDA, KJ · 2017 to 2020
$1.4M
AHRQ HHS R01 HS025177HSRD VA IK6 HX003156
6 · The paper itself

Abstract

introductionThe objective of this study is to identify county-level characteristics that may be high-impact targets for opioid and antibiotic interventions to improve dental prescribing.

methodsPrescriptions during 2012-2017 were extracted from the IQVIA Longitudinal Prescription database. Primary outcomes were yearly county-level antibiotic and opioid prescribing rates. Multivariable negative binomial regression identified associations between prescribing rates and county-level characteristics. All analyses occurred in 2020.

resultsOver time, dental opioid prescribing rates decreased by 20% (from 4.02 to 3.22 per 100 people), whereas antibiotic rates increased by 5% (from 6.85 to 7.19 per 100 people). Higher number of dentists per capita, higher proportion of female residents, and higher proportion of residents aged <65 years were associated with increased opioid rates. Relative to location in the West, location in the Northeast (59%, 95% CI=52, 65) and Midwest (64%, 95% CI=60, 70) was associated with lower opioid prescribing rates. Higher clinician density, median household income, proportion female, and proportion White were all independently associated with higher antibiotic rates. Location in the Northeast (149%, 95% CI=137, 162) and Midwest (118%, 95% CI=111, 125) was associated with higher antibiotic rates. Opioid and antibiotic prescribing rates were positively associated.

conclusionsDental prescribing of opioids is decreasing, whereas dental antibiotic prescribing is increasing. High prescribing of antibiotics is associated with high prescribing of opioids. Strategies focused on optimizing dental antibiotics and opioids are needed given their impact on population health.

Indexed as

Analgesics, OpioidPopulation HealthAnti-Bacterial AgentsDentistsDrug PrescriptionsFemaleHumansPractice Patterns, Physicians'Analgesics, OpioidAnti-Bacterial Agents

Identifiers

PMID33745816
PMCPMC8549405
OpenAlexW3136830133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.