Trial reportBMC neurology2021
Feasibility and adherence to moderate intensity cardiovascular fitness training following stroke: a pilot randomized controlled trial.
Trial report in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07569497 (Co-design of a Physical Activity Maintenance Intervention for People With Stroke), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Co-design of a Physical Activity Maintenance Intervention for People With Stroke
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of nonpharmacological interventions on post-stroke quality of life: a systematic review, meta-analysis, and meta-regression.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Pooled it
- Optimizing physical fitness in chronic stroke patients: the impact of exercise training modality and dosage on maximal and sub-maximal fitness - a systematic review and meta-analysis.Journal of rehabilitation medicine · 2025Pooled it
- Current exercise-based rehabilitation impacts on poststroke exercise capacity, blood pressure, and lipid control: a meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Pooled it
- Effects of different intensity training with a lower limb exoskeleton robot on walking function in people with subacute stroke: a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2026Trial
- Visual and visual-proprioceptive training improve gait via sensory reweighting after chronic stroke: a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2026Trial
- Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-Disabling Stroke or Transient Ischemic Attack (PREVENT Trial): A Randomized Controlled Trial.Neurorehabilitation and neural repair · 2022Trial
- Co-Design of a Physical Activity Maintenance Intervention for People With Stroke: Protocol for a Mixed Methods Study.JMIR research protocols · 2026Article
- Safety and Benefits of Moderate to High Intensity Aerobic Exercise During the Subacute Phase of Stroke: A Systematic Review and Meta-analysis.Archives of rehabilitation research and clinical translation · 2026Review
- Higher Heart Rates During Locomotor High-Intensity Interval Training Are Associated With Gait Asymmetry and Fatigue After Stroke.Cardiopulmonary physical therapy journal · 2025Article
- Resting-State fMRI and Post-Ischemic Stroke Functional Recovery: Unraveling Causality and Predicting Therapeutic Targets.International journal of molecular sciences · 2025Article
- Measuring severe stroke: a scoping review of RCTs.Frontiers in neurology · 2025Review
- High-Intensity Exercise Training Impact on Cardiorespiratory Fitness, Gait Ability, and Balance in Stroke Survivors: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Duration and Efficiency of Combined versus Isolated Aerobic Training Interventions in Post-Stroke Cognition: A Systematic Review.Portuguese journal of public health · 2024Review
- Effects of Assisted Walking Exercise in Chronic Dependent Ambulatory Stroke Survivors: A Mini-Review.Advances in geriatric medicine and research · 2024Article
- Mechanisms and benefits of cardiac rehabilitation in individuals with stroke: emerging role of its impact on improving cardiovascular and neurovascular health.Frontiers in cardiovascular medicine · 2024Review
- Challenge Level Contributes to the Efficacy of Treadmill Interventions after Stroke: A Systematic Review and Meta-Analysis.Brain sciences · 2023Review
- An Intensive Exercise Program Using a Technology-Enriched Rehabilitation Gym for the Recovery of Function in People With Chronic Stroke: Usability Study.JMIR rehabilitation and assistive technologies · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke is a leading cause of disability worldwide and the cardiovascular fitness levels of stroke survivors are diminished to an extent that impairs functioning and activities of daily living performance. While cardiovascular training seems an empirically appropriate intervention, the optimal dosage and intensity of cardiovascular training in stroke survivors remains unclear. The aim was to determine the safety and feasibility of moderate-intensity cardiovascular training following stroke, including measurement of adherence to training.
methodsA pilot, prospective, patient- and assessor-blinded randomised controlled trial conducted in a tertiary, metropolitan hospital-based community rehabilitation centre. Eligibility criteria included ambulant (> 100 m), 6 weeks-12 months post stroke. Moderate-intensity fitness training or control (low-intensity) exercise was offered biweekly for 12 weeks. Outcome measures included adverse events, peak oxygen uptake (VO
resultsFeasibility: Seventy-one (50%) of 141 screened participants were eligible (29% did not agree to participate). Twenty participants (10 intervention, 10 control) were recruited. The median (%; IQR) supervised sessions was 19.5 (81%; 12, 20); and 20 (83%; 19, 22) in the intervention and control groups, respectively. Progression of duration and intensity was limited; mean of 10 sessions to achieve target duration (30 min). There were no adverse events. Baseline peak oxygen uptake (VO
conclusionsModerate-intensity fitness training was safe but achievement of target duration and intensity was challenging for stroke survivors. A definitive adequately-powered randomised trial is required. Alternative fitness training protocols may need to be explored.
trial registrationThe trial protocol was prospectively registered on the Australian New Zealand Clinical Trials Registry ( ACTRN 12613000822785 ) on 25/07/2013.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.