ReviewCartilage2021
Algorithm for Treatment of Focal Cartilage Defects of the Knee: Classic and New Procedures.
Review in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 95 citations in OpenAlex.
- Natural Biomaterials for Osteochondral Repair: From Source to Strategy.Advanced healthcare materials · 2026Review
- Surgical caseload and annual volume influence cartilage treatment strategies in primary anterior cruciate ligament reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Is There a Difference Between Medial and Lateral Femoral Condyle Allografts? An Outcome and Survivorship Analysis.Orthopaedic journal of sports medicine · 2026Article
- Innovative Technologies for Articular Cartilage Repair: Research, Development, and Clinical Translation-A Narrative Review.Journal of functional biomaterials · 2026Review
- Safety and Survival Rate of a Biomimetic Osteochondral Scaffold for the Treatment of Lesions of the Knee Articular Surface.Orthopaedic journal of sports medicine · 2026Article
- Matrix-induced autologous chondrocytes implantation for a large iatrogenic osteochondral defect of the knee: A case report.Trauma case reports · 2026Article
- Surface-based treatment options for cartilage lesions of the knee.Annals of joint · 2026Review
- Algorithm-Based Surgical Decision-Making for Focal Knee Cartilage Defects: A Pragmatic Clinical Framework with Illustrative Cases.Orthopedic reviews · 2026Article
- Osteochondral Allograft Transplantation of the Femoral Head via Surgical Hip Dislocation: Survivorship and Patient Reported Outcome Measures at Minimum 2-Year Follow-Up.Orthopaedic journal of sports medicine · 2025Article
- Co-delivery of NGF and BMP-2 via thermosensitive pluronic F127 hydrogel enhances chondrogenesis and cartilage repair.Scientific reports · 2025Article
- Autologous Osteochondral Transplantation in Large Osteochondral Defects-A Follow-Up of 52 Patients After Knee Joint Resurfacing.Journal of clinical medicine · 2025Article
- Functional outcome after arthroscopic mosaicplasty for localised osteochondral defects in the knee.Medical journal, Armed Forces India · 2025Article
- Autologous bone grafting combined with spheroid-based matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: Good clinical outcomes alongside abnormal postoperative gait patterns.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Article
- Biochemical and Biomechanical Properties of Scaffold-Free Hyaline Cartilage Generated Under Dynamic Conditions.International journal of molecular sciences · 2025Article
- Single BMSC-derived cartilage organoids for gradient heterogeneous osteochondral regeneration by leveraging native vascular microenvironment.Journal of nanobiotechnology · 2025Article
- Arthroscopic Implantation of a Cell-Free Bilayer Scaffold for the Treatment of Knee Chondral Lesions: A 2-Year Prospective Study.Cartilage · 2025Article
- Comparison of Clinical, Radiologic, and Arthroscopic Outcomes Between the Microfracture and Microdrilling Techniques for Articular Cartilage Defects in Medial Opening-Wedge High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2025Article
- Functional Outcomes of Nuts-in-Jelly Mosaicplasty.Indian journal of orthopaedics · 2025Article
- Management of Isolated Tibial Plateau Defect in the Setting of Anterior Cruciate Ligament Reconstruction and Meniscus Repair: A Case Report and Review of the Literature.Case reports in orthopedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 10 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo create a treatment algorithm for focal grade 3 or 4 cartilage defects of the knee using both classic and novel cartilage restoration techniques.
designA comprehensive review of the literature was performed highlighting classic as well as novel cartilage restoration techniques supported by clinical and/or basic science research and currently being employed by orthopedic surgeons.
resultsThere is a high level of evidence to support the treatment of small to medium size lesions (<2-4 cm
conclusionsNumerous techniques exist for the orthopedic surgeon treating focal cartilage defects of the knee. Treatment strategies should be based on lesion size, lesion location, subchondral bone involvement, and the level of evidence supporting each technique in the literature.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.