Evidence map›Paper›PMID 33745198›Full record

ArticleJournal of cellular and molecular medicine2021

Bmi1 regulate tooth and mandible development by inhibiting p16 signal pathway.

Ying Yin, Nan Zhou, Hui Zhang, Xiuliang Dai, Xianhui Lv, Ning Chen, Dengshun Miao, Qingang Hu

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ying YinNanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.ORCID 0000-0002-5547-1120
Nan ZhouNanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Hui ZhangNanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Xiuliang DaiReproductive Center, Nanjing Medical University Affiliated Changzhou Maternal and Child Health Care Hospital, Changzhou, China.
Xianhui LvDepartment of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Ning ChenInstitute of Stomatology, Nanjing Medical University, Nanjing, China.
Dengshun MiaoDepartment of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Qingang HuNanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Nanjing Medical University · CNChangzhou No.2 People's Hospital · CNNanjing Municipal Center for Disease Control And Prevention · CNPlastic Surgery Hospital · CN

Funding

Changzhou Health Committee Funded Young Investigator Training Project CZQM2020094Medical Science and Technology Progress Project of Nanjing YKK16161National Natural Science Foundation of China 81730066National Natural Science Foundation of China 81800933Natural Science Foundation of Jiangsu Province BK20180137
6 · The paper itself

Abstract

To determine whether the deletion of p16 can correct tooth and mandible growth retardation caused by Bmi1 deficiency, we compared the tooth and mandible phenotypes of homozygous p16-deficient (p16

Indexed as

OsteogenesisAnimalsCell CycleCell ProliferationCyclin-Dependent Kinase Inhibitor p16MandibleMiceMice, KnockoutOsteoblastsPolycomb Repressive Complex 1Proto-Oncogene ProteinsSignal TransductionToothBmi1 protein, mouseCyclin-Dependent Kinase Inhibitor p16Polycomb Repressive Complex 1Proto-Oncogene ProteinsBmi1developmentmandiblep16tooth

Identifiers

PMID33745198
PMCPMC8093977
OpenAlexW3138636870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.