ArticlePediatric nephrology (Berlin, Germany)2021
Acute kidney injury in children hospitalized for community acquired pneumonia.
Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 37 citations in OpenAlex.
- Development and bootstrap-based internal validation of a dynamic model for predicting acute kidney injury after day-3 reassessment in children with severe community-acquired pneumonia.Translational pediatrics · 2026Article
- Using health systems evidence to study and predict long-term outcomes of childhood acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2026Article
- Prevalence and risk factors for acute kidney injury at the diagnosis of juvenile idiopathic arthritis in children and its long-term implications for kidney health.Pediatric nephrology (Berlin, Germany) · 2026Article
- Prevalence and factors associated with acute kidney injury in children presenting to the emergency department with a first tonic-clonic seizure: an exploratory study.European journal of pediatrics · 2026Article
- A nomogram model for predicting acute kidney injury in critically ill patients with upper gastrointestinal bleeding: a study based on the MIMIC-IV database and external validation.BMC gastroenterology · 2026Article
- Cystatin C for predicting acute kidney injury in critically ill children with bacterial infections: a retrospective cohort study.BMJ paediatrics open · 2026Article
- Incidence, clinical characteristics, and risk factors of acute kidney injury in patients withFrontiers in cellular and infection microbiology · 2026Article
- Treatment protocol for pneumonia with acute kidney injury: effects of ulinastatin combined with CRRT on inflammatory factors and renal function in patients.Frontiers in medicine · 2026Article
- Acute kidney injury in children and adolescents admitted for pneumonia in the Philippines.Pediatric nephrology (Berlin, Germany) · 2025Article
- The relevance of acute kidney injury in dehydrated children.Frontiers in pediatrics · 2025Review
- Early goal-directed renal replacement therapy in severe pneumonia associated acute kidney injury.Renal failure · 2024Article
- Heart rate to identify non-febrile children with dehydration and acute kidney injury in emergency department: a prospective validation study.European journal of pediatrics · 2024Article
- Changes in urinary renal injury markers in children with Mycoplasma pneumoniae pneumonia and a prediction model for related early renal injury.Italian journal of pediatrics · 2024Article
- Acute Kidney Injury in Children: A Focus for the General Pediatrician.Children (Basel, Switzerland) · 2024Review
- Acute kidney injury in infants hospitalized for viral bronchiolitis.European journal of pediatrics · 2023Article
- Acute and chronic kidney complications in children with type 1 diabetes mellitus.Pediatric nephrology (Berlin, Germany) · 2023Review
- Factors Associated with Acute Kidney Injury among Children with Severe Malaria at Kiryandongo General Hospital, Uganda.International journal of pediatrics · 2023Article
- The ratio of monocytes to lymphocytes multiplying platelet predicts incidence of pulmonary infection-related acute kidney injury.European journal of medical research · 2022Article
- Diagnostic Performance of the Acute Kidney Injury Baseline Creatinine Equations in Children and Adolescents with Type 1 Diabetes Mellitus Onset.Diagnostics (Basel, Switzerland) · 2022Article
- Diagnostic Performance of Height-Estimated Baseline Creatinine in Diagnosing Acute Kidney Injury in Children with Type 1 Diabetes Mellitus Onset.Children (Basel, Switzerland) · 2022Article
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8 authors at 1 institution in 1 country.
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Abstract
backgroundAcute kidney injury (AKI) enhances the risk of later chronic kidney disease. Significant prevalence of AKI is reported in adults with community acquired pneumonia (CAP). We investigated prevalence of and prognostic factors for AKI in children hospitalized for CAP.
methodsWe retrospectively collected clinical and biochemical data of 186 children (48.4% male; mean age 2.6±2.4 years) hospitalized for X-ray-confirmed CAP. AKI was defined according to Kidney Disease/Improving Global Outcomes creatinine criteria. We considered as basal serum creatinine the value estimated with Hoste (age) equation assuming basal eGFR were median age-based eGFR normative values for children ≤ 2 years of age and eGFR= 120 mL/min/1.73m
resultsAKI was found in 38/186 (20.4%) patients. No patient required hemodialysis nor reached AKI stage 3, 5 (2.7%) reached AKI stage 2, and 33 (17.7%) AKI stage 1. Mean length of stay was 6.0±1.7, 6.9±2.3, and 12.2±1.5 days, for patients without AKI, stage 1 AKI, and stage 2 AKI (p < 0.001), respectively. Duration of symptoms before hospitalization (OR 1.2; 95%CI 1.09-1.43; p = 0.001), severe pneumonia (OR 11.9; 95%CI 4.3-33.3; p < 0.001), and serum C-reactive protein levels (OR 1.1; 95%CI 1.04-1.23; p = 0.004) were independent AKI predictors.
conclusionsAbout 1/5 of children hospitalized for CAP present a generally mild AKI with a longer stay for those with more severe AKI. Attention should be paid to kidney health of children with CAP especially in presence of higher duration of symptoms before hospitalization, severe pneumonia and higher serum CRP levels.
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