Evidence map›Paper›PMID 33745035›Full record

ReviewInternational ophthalmology2021

Laser flare and cell photometry to measure inflammation after cataract surgery: a tool to predict the risk of cystoid macular edema.

Michele De Maria, Marco Coassin, Danilo Iannetta, Luigi Fontana

Abstract readReview
PubMed Publisher
In one paragraph

Review in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Michele De MariaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Viale Risorgimento 80, 42122, Reggio Emilia, Italy.
Marco CoassinOphthalmology, University Campus Bio-Medico of Rome, Rome, Italy.
Danilo IannettaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Viale Risorgimento 80, 42122, Reggio Emilia, Italy.
Luigi FontanaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Viale Risorgimento 80, 42122, Reggio Emilia, Italy. luifonta@gmail.com.ORCID http://orcid.org/0000-0003-3877-0417
Azienda Sanitaria Unità Locale di Reggio Emilia · ITUniversità Campus Bio-Medico · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo review the current adoption of laser flare and cell photometry (LFCP) in the setting of modern cataract surgery to analyze inflammation aiming to identify evidence of a correlation between LFCP values and the risk of cystoid macular edema (CME) development.

methodsAn extensive PubMed literature search was performed to review all the published studies investigating inflammation by LFCP after uncomplicated phacoemulsification. The following keywords were used: cataract surgery, cystoid macular edema, anterior chamber inflammation, laser flare, and cell photometry.

resultsSeventy-eight original articles investigating inflammation by LFCP were selected. Macula alterations were searched in 12 (15%) trials, by optical coherence tomography or fluorescein angiography in 11 (14%) and 1 (1%) studies, respectively. Among them, 9 (12%) papers investigated the correlation between LFCP values and cystic changes to the macula: 7 (9%) and 2 (3%) studies identified a positive and negative correlation, respectively. Three (4%) papers did not perform any correlation analysis.

conclusionCME, as a consequence of uncontrolled postoperative inflammation, is a common cause for unfavorable visual outcomes following uncomplicated phacoemulsification with IOL implantation. After surgery, intraocular inflammation is generally assessed by qualitative methods. Although well-established and practical in uveitis, they are inadequate to detect the modest inflammatory response that usually occurs after uneventful phacoemulsification. LFCP correlate with the chance of macula alteration after surgery and higher the values higher the risk of CME. The quantitative analysis of intraocular inflammation by LFCP after cataract surgery might be a tool to predict the risk of pseudophakic CME.

Indexed as

CataractMacular EdemaPhacoemulsificationHumansInflammationLasersPhotometryPostoperative ComplicationsTomography, Optical CoherenceCataractCystoid macular edemaInflammationLaser flare and cell photometryPhacoemulsification

Identifiers

PMID33745035
OpenAlexW3138737203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.