Evidence map›Paper›PMID 33744992›Full record

ArticleEuropean radiology2021

Low keV portal venous phase as a surrogate for pancreatic phase in a pancreatic protocol dual-energy CT: feasibility, image quality, and lesion conspicuity.

Yoshifumi Noda, Toru Tochigi, Anushri Parakh, Evita Joseph, Peter F Hahn, Avinash Kambadakone

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Yoshifumi NodaDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270, 55 Fruit Street, White 270, Boston, MA, 02114, USA.
Toru TochigiDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270, 55 Fruit Street, White 270, Boston, MA, 02114, USA.
Anushri ParakhDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270, 55 Fruit Street, White 270, Boston, MA, 02114, USA.
Evita JosephDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270, 55 Fruit Street, White 270, Boston, MA, 02114, USA.
Peter F HahnDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270, 55 Fruit Street, White 270, Boston, MA, 02114, USA.
Avinash KambadakoneDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, White 270, 55 Fruit Street, White 270, Boston, MA, 02114, USA. akambadakone@mgh.harvard.edu.ORCID http://orcid.org/0000-0001-6714-9190
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the feasibility of a proposed pancreatic protocol CT generated from portal-venous phase (PVP) dual-energy CT (DECT) acquisition and its impact on image quality, lesion conspicuity, and arterial visualization/involvement.

methodsWe included 111 patients (mean age, 66.8 years) who underwent pancreatic protocol DECT (pancreatic phase, PP, and PVP). The original DECT acquisition was used to create two data sets-standard protocol (50 keV PP/65 keV PVP) and proposed protocol (40 keV/65 keV PVP). Three reviewers evaluated the two data sets for image quality, lesion conspicuity, and arterial visualization/involvement using a 5-point scale. The signal-to-noise ratio (SNR) of pancreas and lesion-to-pancreas contrast-to-noise ratio (CNR) was calculated. Qualitative scores, quantitative parameters, and dose-length product (DLP) were compared between standard and proposed protocols.

resultsThe image quality, SNR of pancreas, and lesion-to-pancreas CNR of the standard and proposed protocol were comparable (p = 0.11-1.00). Lesion conspicuity was comparable between the standard and proposed protocols for pancreatic ductal adenocarcinoma (p = 0.55) and pancreatic cysts (p = 0.28). The visualization of larger arteries and arterial involvement were comparable between the two protocols (p = 0.056-1.00) while the scores were higher for smaller vessels in the standard protocol (p < 0.0001-0.0015). DLP of the proposed protocol (670.4 mGy·cm) showed a projected 42% reduction than the standard protocol (1145.9 mGy·cm) (p < 0.0001).

conclusionPancreatic protocol CT generated from a single PVP DECT acquisition is feasible and could potentially be an alternative to the standard pancreatic protocol with PP and PVP. KEY POINTS: • The lesion conspicuity for focal pancreatic lesions was comparable between the proposed protocol and standard dual-phase pancreatic protocol CT. • Qualitative and quantitative image assessments were almost comparable between two protocols. • The radiation dose of a proposed protocol showed a projected 42% reduction from the conventional protocol.

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsRadiography, Dual-Energy Scanned ProjectionAgedContrast MediaFeasibility StudiesHumansPancreasRadiation DosageRadiographic Image Interpretation, Computer-AssistedSignal-To-Noise RatioTomography, X-Ray ComputedContrast MediaCancer screeningMultidetector-row computed tomographyPancreatic neoplasmsRadiation dosage

Identifiers

PMID33744992
OpenAlexW3137364971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.