ArticleJournal of neurology2021
Diagnostic value of video-oculography in progressive supranuclear palsy: a controlled study in 100 patients.
Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Advanced Eye Movement Features Measured by Quantitative Oculography as Candidate Biomarkers for Progressive Supranuclear Palsy.Diagnostics (Basel, Switzerland) · 2026Review
- Global Rather Than Vertical-Selective Saccadic Abnormalities in Progressive Supranuclear Palsy.Annals of clinical and translational neurology · 2026Article
- VR-based quantitative oculomotor analysis and association with regional brain atrophy in MSA.Journal of Parkinson's disease · 2026Article
- No anti-IgLON5 antibody in carefully diagnosed PSP patients with "atypical" or variant clinical features.Parkinsonism & related disorders · 2025Article
- Review
- Eye movement abnormalities in Parkinson's disease motor subtypes: a video-oculographic study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Eye movement abnormalities in normal pressure hydrocephalus: a video-oculographic study.Journal of neurology · 2025Article
- Joint examination of reflexive vertical saccades and small involuntary fixational saccades improves the classification of patients with progressive supranuclear palsy (PSP): a ROC study.Experimental brain research · 2025Article
- Systematic assessment of square-wave jerks in progressive supranuclear palsy: a video-oculographic study.Journal of neurology · 2024Article
- Asymmetry in Atypical Parkinsonian Syndromes-A Review.Journal of clinical medicine · 2024Review
- Clinical value of video oculomotor evaluation in the differential diagnosis of multiple system atrophy and Parkinson's disease.Brain and behavior · 2024Article
- Smartphone video nystagmography using convolutional neural networks: ConVNG.Journal of neurology · 2023Article
- Magnetic Resonance Planimetry in the Differential Diagnosis between Parkinson's Disease and Progressive Supranuclear Palsy.Brain sciences · 2022Review
- Multimodal in vivo staging in amyotrophic lateral sclerosis using artificial intelligence.Annals of clinical and translational neurology · 2022Article
- Segmental Alterations of the Corpus Callosum in Progressive Supranuclear Palsy: A Multiparametric Magnetic Resonance Imaging Study.Frontiers in aging neuroscience · 2021Article
Corrections and comments
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe eponymous feature of progressive supranuclear palsy (PSP) is oculomotor impairment which is one of the relevant domains in the Movement Disorder Society diagnostic criteria.
objectiveWe aimed to investigate the value of specific video-oculographic parameters for the use as diagnostic markers in PSP.
methodsAn analysis of video-oculography recordings of 100 PSP patients and 49 age-matched healthy control subjects was performed. Gain of smooth pursuit eye movement and latency, gain, peak eye velocity, asymmetry of downward and upward velocities of saccades as well as rate of saccadic intrusions were analyzed.
resultsVertical saccade velocity and saccadic intrusions allowed for the classification of about 70% and 56% of the patients, respectively. By combining both parameters, almost 80% of the PSP patients were covered, while vertical velocity asymmetry was observed in approximately 34%. All parameters had a specificity of above 95%. The sensitivities were lower with around 50-60% for the velocity and saccadic intrusions and only 27% for vertical asymmetry.
conclusionsIn accordance with oculomotor features in the current PSP diagnostic criteria, video-oculographic assessment of vertical saccade velocity and saccadic intrusions resulted in very high specificity. Asymmetry of vertical saccade velocities, in the opposite, did not prove to be useful for diagnostic purposes.
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