Evidence map›Paper›PMID 33744848›Full record

ArticleAging2021

lncRNA OGFRP1 promotes tumor progression by activating the AKT/mTOR pathway in human gastric cancer.

Jingzhou Zhang, Xiujuan Xu, Junfeng Yin, Jiaqi Tang, Nan Hu, Yidong Hong, Ziyan Song, Baoxiang Bian, Fenglei Wu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jingzhou ZhangDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Xiujuan XuDepartment of Radiation Oncology, Lianyungang Second People's Hospital, Lianyungang, China.
Junfeng YinDepartment of General Surgery, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
Jiaqi TangDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Nan HuDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Yidong HongDeparment of Oncology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Ziyan SongDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Baoxiang BianDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Fenglei WuDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Nanjing Medical University · CNThe First People’s Hospital of Lianyungang · CNJiangsu University · CNXian Yang Central Hospital · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As biomolecules of great clinical value, lncRNAs play a crucial role as regulators in the processes of tumor origin, metastasis, and recurrence. Thus, lncRNAs are urgently needed for research in gastric cancer. We elucidated the specific function of OGFRP1, both

Indexed as

AnimalsCell Line, TumorCell ProliferationDisease ProgressionGastric MucosaGene Knockdown TechniquesHumansMicePhosphorylationProto-Oncogene Proteins c-aktRNA, Long NoncodingSignal TransductionStomachStomach NeoplasmsTOR Serine-Threonine KinasesProto-Oncogene Proteins c-aktRNA, Long NoncodingTOR Serine-Threonine Kinasesapoptosisgastric cancerlncRNAOGFRP1proliferation

Identifiers

PMID33744848
PMCPMC8064230
OpenAlexW3137491365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.