Evidence map›Paper›PMID 33744761›Full record

ArticleBiochemical and biophysical research communications2021

Discrete binding patterns of two heparin-reactive proteins, basic fibroblast growth factor and peptide p5R, in amyloid-laden and healthy mice.

Emily B Martin, Robert Donnell, Tina Richey, Alan Stuckey, Stephen J Kennel, Jonathan S Wall

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Emily B MartinDepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA. Electronic address: Emartin@utmck.edu.
Robert DonnellDepartment of Biomedical and Diagnostic Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, TN, USA.
Tina RicheyDepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
Alan StuckeyDepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
Stephen J KennelDepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
Jonathan S WallDepartment of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
University of Tennessee at Knoxville · USKnoxville College · USUniversity of Tennessee Medical Center · US

Funding

Preclinical Diagnostic Imaging of AmyloidR01DK079984 · NIDDK · UNIVERSITY OF TENNESSEE KNOXVILLE · PI WALL, JONATHAN S · 2009 to 2016
$3.4M
NIDDK NIH HHS R01 DK079984
6 · The paper itself

Abstract

Peptide p5R is a synthetic, polybasic, heparin-binding peptide that preferentially reacts with amyloid deposits in vivo and in tissue sections. Basic fibroblast growth factor (bFGF

Indexed as

AmyloidAmyloidosisAnimalsAutoradiographyFibroblast Growth Factor 2HeparinIodine RadioisotopesLiverMiceMice, Inbred BALB CMice, TransgenicMolecular StructurePeptidesProtein DomainsSingle Photon Emission Computed Tomography Computed TomographySpleenAmyloidFibroblast Growth Factor 2HeparinIodine-125Iodine RadioisotopesPeptidesAmyloidosisBasic fibroblast growth factorBiodistributionHeparinPeptide p5RSPECT/CT imaging

Identifiers

PMID33744761
PMCPMC8035312
OpenAlexW3139482069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.