Evidence map›Paper›PMID 33744430›Full record

ArticleOsteoarthritis and cartilage2021

Dietary patterns and risk of developing knee osteoarthritis: data from the osteoarthritis initiative.

C Xu, T Liu, J B Driban, T McAlindon, C B Eaton, B Lu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

  • Commented on by
    2021
5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

C XuDivision of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Rutgers University, School of Public Health, Department of Biostatistics and Epidemiology, New Brunswick, NJ, USA.
T LiuDivision of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu, PR China.
J B DribanDivision of Rheumatology, Allergy, and Immunology, Tufts Medical Center, Boston, MA, USA.
T McAlindonDivision of Rheumatology, Allergy, and Immunology, Tufts Medical Center, Boston, MA, USA.
C B EatonBrown University Center for Primary Care and Prevention, Pawtucket, RI, USA; Departments of Family Medicine and Epidemiology, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
B LuDivision of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: blu1@bwh.harvard.edu.
Brigham and Women's Hospital · USTufts Medical Center · USBrown University · USRutgers, The State University of New Jersey · US

Funding

Metabolites of Dietary Intake and Risk of Knee OsteoarthritisR01AR074447 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LU, BING · 2019 to 2022
$2.6M
NIAMS NIH HHS R01 AR074447
6 · The paper itself

Abstract

objectiveSome studies have examined the association between dietary factors and risk of knee osteoarthritis (OA). We aimed to examine the prospective association of major dietary patterns with the risk of developing knee OA.

methodWe followed 2,842 participants in Osteoarthritis Initiative (OAI) aged 45-79 years and with at least one knee free from radiographic knee OA at baseline for up to 72 months. We defined knee OA incidence as Kellgren and Lawrence grade ≥2 during follow-up visits. Using principal component analysis, Western and prudent dietary patterns were derived. Cox proportional hazards models were used to assess the association between dietary patterns and incident knee OA.

resultsAmong study participants, 385 (418 knees) developed knee OA within 72 months. Following a Western dietary pattern was associated with an increased risk of knee OA (HR

conclusionFollowing a Western diet was associated with increased risk of knee OA, whereas following a prudent pattern was associated with a reduced risk of knee OA. The associations were partially mediated through BMI.

Indexed as

AgedDietFemaleHumansMaleMiddle AgedOsteoarthritis, KneeRisk FactorsDietary patternsKnee osteoarthritis riskPrudent dietWestern diet

Identifiers

PMID33744430
PMCPMC8318673
OpenAlexW3139354579

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.