Evidence map›Paper›PMID 33744303›Full record

ArticleThe Journal of infection2021

Retrospective serosurveillance for anti-SARS-CoV-2 immunoglobulin during a time of low prevalence: A cautionary tale.

Paul William Bird, Christopher Holmes, Oliver Fletcher, Vinay Badhwar, Oliver Toovey, Julian Wei-Tze Tang

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in The Journal of infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Paul William BirdClinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, LE1 5WW Leicester, United Kingdom. Electronic address: julian.tang@uhl-tr.nhs.uk.
Christopher HolmesClinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, LE1 5WW Leicester, United Kingdom; Respiratory Sciences, University of Leicester, LE1 9HN, United Kingdom.
Oliver FletcherClinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, LE1 5WW Leicester, United Kingdom.
Vinay BadhwarIntensive Care Unit, University Hospitals of Leicester NHS Trust, Leicester, Royal Infirmary, LE1 5WW Leicester, United Kingdom.
Oliver TooveyClinical Virology, University Hospitals 24 of Leicester NHS Trust, Leicester, Royal Infirmary, LE1 5WW Leicester, United Kingdom.
Julian Wei-Tze TangRespiratory Sciences, University of Leicester, LE1 9HN, United Kingdom.
University Hospitals of Leicester NHS Trust · GBUniversity of Leicester · GBLeicester Royal Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a retrospective screening of 428 serum samples for anti-SARS-CoV-2  immunoglobulin during a period of low prevalence. Employing two different serological tests yielded discrepant results for 10 samples; highlighting an increased risk of potential  false positive results and the need for further confirmatory testing before publication of data.

Indexed as

COVID-19SARS-CoV-2BrazilFalse Positive ReactionsHumansImmunoglobulinsPrevalenceRetrospective StudiesSensitivity and SpecificityImmunoglobulinsLow prevalenceSARS-CoV-2Serological testing

Identifiers

PMID33744303
PMCPMC7968146
OpenAlexW3138288847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.